SCHEMBL8765490

SCHEMBL8765490

O=C(O)CN(CC(=O)O)Cc1cccc(-c2cccc(CN(CC(=O)O)CC(=O)O)n2)n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.38
ALOX15 P16050 3/20 0.38
TSHR P16473 3/20 0.38
CYP2C19 P33261 2/20 0.38
HIF1A Q16665 1/20 0.38
EYA2 O00167 1/20 0.37
APP P05067 1/20 0.37
ACE P12821 1/20 0.37
AOC3 Q16853 1/20 0.36
PPARG P37231 3/20 0.36
PPARA Q07869 3/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
KDM4E B2RXH2 2/20 0.35
LMNA P02545 1/20 0.35
CHRM2 P08172 1/20 0.35
ADRA2A P08913 1/20 0.35
DRD1 P21728 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6161950 0.98 TDP1 (0.37) TDP1ALOX15TSHRCYP2C19HIF1A
SCHEMBL14496263 0.92 ALOX15 (0.40) TDP1ALOX15TSHRCYP2C19HIF1A
SCHEMBL377313 0.90 NPSR1 (0.41) TDP1ALOX15TSHRCYP2C19HIF1A
SCHEMBL11303061 0.88 AOC3 (0.36) TDP1ALOX15TSHRCYP2C19HIF1A
SCHEMBL23627732 0.87 MEP1B (0.38) HDAC1HDAC2KDM4EEPORMEP1A
SCHEMBL13997749 0.85 LTB4R (0.39) PPARGPPARAKDM4EMEP1B
SCHEMBL13492109 0.83 SMPD2 (0.36) TDP1ALOX15TSHRCYP2C19HIF1A
SCHEMBL14496261 0.82 TDP1 (0.43) TDP1ALOX15TSHRCYP2C19HIF1A
SCHEMBL15483848 0.82 TDP1 (0.46) TDP1ALOX15TSHRCYP2C19HIF1A
SCHEMBL13997750 0.82 LTB4R (0.41) AOC3PPARGPPARAHDAC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0664819-B1 CHELATING POLYMERS NYCOMED IMAGING AS (NO) 1997-08-06 EP claimed
US-5583206-A MODIFIED POLYALKYLENE OXIDES STERLING WINTHROP (US) 1996-12-10 US claimed
EP-4610269-A1 UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR (UPAR) LIGANDS FOR DIAGNOSTIC OR THERAPEUTIC USE 3B Pharmaceuticals GmbH (DE) 2025-09-03 EP disclosed
EP-4455159-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS WITH BIO-DISTRIBUTION MODIFIER 3B Pharmaceuticals GmbH (DE) 2024-10-30 EP disclosed
US-9505961-B2 Acrylic pressure sensitive adhesive composition, protection film including the same, polarizer and liquid crystal display LG CHEM, LTD. (KR) 2016-11-29 US disclosed
US-9505961-B2 Acrylic pressure sensitive adhesive composition, protection film including the same, polarizer and liquid crystal display LG CHEM, LTD. (KR) 2016-11-29 US disclosed
US-9499725-B2 Acrylic pressure-sensitive adhesive compositions LG CHEM, LTD. (KR) 2016-11-22 US disclosed
US-9499725-B2 Acrylic pressure-sensitive adhesive compositions LG CHEM, LTD. (KR) 2016-11-22 US disclosed
US-9383481-B2 Liquid crystal display LG CHEM, LTD. (KR) 2016-07-05 US disclosed
US-9383481-B2 Liquid crystal display LG CHEM, LTD. (KR) 2016-07-05 US disclosed
US-8717518-B2 Polarization plate and liquid crystal display LG CHEM, LTD. (KR) 2014-05-06 US disclosed
US-20110109849-A1 ACRYLIC COMPOSITION FOR OPTICAL MEMBERS, PROTECTIVE FILM FOR OPTICAL MEMBERS, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY LG CHEM, LTD. (KR) 2011-05-12 US disclosed
US-7863360-B2 Acrylic pressure sensitive adhesive compositions LG CHEM, LTD. (KR) 2011-01-04 US disclosed
US-7863360-B2 Acrylic pressure sensitive adhesive compositions LG CHEM, LTD. (KR) 2011-01-04 US disclosed
US-20100209631-A1 ACRYLIC PRESSURE SENSITIVE ADHESIVE COMPOSITION, PROTECTION FILM INCLUDING THE SAME, POLARIZER AND LIQUID CRYSTAL DISPLAY LG CHEM, LTD. (KR) 2010-08-19 US disclosed
US-20100209631-A1 ACRYLIC PRESSURE SENSITIVE ADHESIVE COMPOSITION, PROTECTION FILM INCLUDING THE SAME, POLARIZER AND LIQUID CRYSTAL DISPLAY LG CHEM, LTD. (KR) 2010-08-19 US disclosed
US-20100188620-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS LG CHEM, LTD. (KR) 2010-07-29 US disclosed
US-20100188620-A1 ACRYLIC PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS LG CHEM, LTD. (KR) 2010-07-29 US disclosed
US-20070026407-A1 Novel fine fluorescent particle WASEDA UNIVERSITY (JP) 2007-02-01 US disclosed
US-5696240-A Macrocyclic complexes of yttrium, the lanthanides and the actinides having peripheral coupling functionalities VALLARINO LIDIA M (US) 1997-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070026407-A1 Novel fine fluorescent particle SPECC1L, RAB5IF, NSFL1C TDP1 3726/4885ALOX15 4178/4885TSHR 3828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.