Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14496930 | 0.85 | LMNA (0.37) | LMNAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL14497144 | 0.83 | SENP3 (0.42) | POLBCYP2D6MAPTMEN1KMT2A | |
| SCHEMBL14497459 | 0.79 | POLB (0.51) | POLBCYP2D6LMNARPS6KA3MAPT | |
| SCHEMBL2938133 | 0.79 | LMNA (0.68) | POLBCYP2D6LMNARPS6KA3MAPT | |
| SCHEMBL2938128 | 0.79 | LMNA (0.68) | POLBCYP2D6LMNARPS6KA3MAPT | |
| SCHEMBL14515976 | 0.75 | POLB (0.44) | POLBCYP2D6LMNARPS6KA3MAPT | |
| SCHEMBL14497127 | 0.74 | KMT2A (0.44) | POLBLMNAMAPTMEN1KMT2A | |
| SCHEMBL3422880 | 0.74 | POLB (0.53) | POLBCYP2D6LMNARPS6KA3MAPT | |
| SCHEMBL18624977 | 0.72 | POLB (0.83) | POLBCYP2D6LMNARPS6KA3PHLPP2 | |
| SCHEMBL28560987 | 0.72 | POLB (0.83) | POLBCYP2D6LMNARPS6KA3PHLPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7232467-B2 | Dyeing hair with capped diazonium compound; intense, striking coloration; light, shampoo and rub fastness; storage stability; nondamaging, nonstaining | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-06-19 | — | — | US | disclosed |
| US-7232467-B2 | Dyeing hair with capped diazonium compound; intense, striking coloration; light, shampoo and rub fastness; storage stability; nondamaging, nonstaining | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-06-19 | — | — | US | disclosed |