Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.65 |
| ▸ | GBA1 | P04062 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | APLNR | P35414 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1443432 | 0.88 | MAPT (0.65) | MAPTNPSR1GBA1ALOX15HTT | |
| SCHEMBL14503296 | 0.84 | MAPT (0.63) | MAPTNPSR1GBA1LMNAPOLB | |
| SCHEMBL5380866 | 0.82 | MAPT (0.49) | MAPTNPSR1GBA1LMNATSHR | |
| SCHEMBL13326030 | 0.78 | GBA1 (0.61) | MAPTNPSR1GBA1LMNAPOLB | |
| SCHEMBL14504429 | 0.78 | NPSR1 (0.56) | MAPTNPSR1GBA1LMNAPOLB | |
| SCHEMBL14503314 | 0.77 | LMNA (0.58) | MAPTNPSR1GBA1LMNAPOLB | |
| SCHEMBL11961929 | 0.76 | MEN1 (0.58) | MAPTLMNAALOX15HTTMAPK1 | |
| SCHEMBL23852696 | 0.75 | APLNR (0.59) | MAPTLMNATSHRALOX15HTT | |
| SCHEMBL18062214 | 0.75 | APLNR (0.59) | MAPTLMNATSHRALOX15HTT | |
| SCHEMBL14504152 | 0.74 | LMNA (0.53) | MAPTNPSR1GBA1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |