Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | ITK | Q08881 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | TTK | P33981 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14503628 | 0.92 | MAPT (0.49) | PTGS2SCN9AITKAURKAKIT | |
| SCHEMBL14503143 | 0.92 | PTGS2 (0.56) | PTGS2SERPINE1CA12CA1CA2 | |
| SCHEMBL14503227 | 0.92 | PTGS2 (0.56) | PTGS2SERPINE1CA12CA1CA2 | |
| SCHEMBL5392099 | 0.88 | SCN9A (0.42) | SERPINE1CA12CA1CA2CA9 | |
| SCHEMBL14503584 | 0.86 | ALDH1A1 (0.51) | PTGS2SERPINE1CA12CA1CA2 | |
| SCHEMBL14503582 | 0.85 | PTGS2 (0.51) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL14503697 | 0.85 | CA12 (0.49) | PTGS2SERPINE1CA12CA1CA2 | |
| SCHEMBL14503666 | 0.84 | CA12 (0.49) | PTGS2SERPINE1CA12CA1CA2 | |
| SCHEMBL14503407 | 0.84 | MEN1 (0.52) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL14503191 | 0.83 | PTGS2 (0.57) | PTGS2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |