Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 5/20 | 0.49 |
| ▸ | CA1 | P00915 | 5/20 | 0.49 |
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | CA9 | Q16790 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14503700 | 0.88 | L3MBTL1 (0.54) | CA12CA1CA2CA9POLB | |
| SCHEMBL14503521 | 0.87 | PTGS2 (0.52) | BRPF1CA12CA1CA2CA9 | |
| SCHEMBL14504245 | 0.87 | CA12 (0.48) | BRPF1CA12CA1CA2CA9 | |
| SCHEMBL5392619 | 0.87 | BRPF1 (0.46) | BRPF1CA12CA1CA2CA9 | |
| SCHEMBL14504249 | 0.86 | CA1 (0.47) | BRPF1CA12CA1CA2CA9 | |
| SCHEMBL14504212 | 0.83 | CA12 (0.51) | CA12CA1CA2CA9POLB | |
| SCHEMBL14504254 | 0.83 | NPSR1 (0.54) | CA12CA1CA2CA9NPSR1 | |
| SCHEMBL14505167 | 0.82 | PTGS2 (0.53) | BRPF1CA12CA1CA2CA9 | |
| SCHEMBL14504247 | 0.82 | CA1 (0.45) | BRPF1CA12CA1CA2CA9 | |
| SCHEMBL14504496 | 0.81 | BRPF1 (0.45) | BRPF1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |