Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.47 |
| ▸ | CA2 | P00918 | 6/20 | 0.47 |
| ▸ | CA12 | O43570 | 5/20 | 0.47 |
| ▸ | CA9 | Q16790 | 5/20 | 0.47 |
| ▸ | AKT1 | P31749 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14504245 | 0.97 | CA12 (0.48) | CA1CA2CA12CA9AKT1 | |
| SCHEMBL14504203 | 0.88 | PTGS2 (0.49) | CA1CA2CA12CA9SMN1; SMN2 | |
| SCHEMBL5400741 | 0.88 | AKT1 (0.44) | CA1CA2CA12CA9AKT1 | |
| SCHEMBL14504247 | 0.86 | CA1 (0.45) | CA1CA2CA12CA9SMN1; SMN2 | |
| SCHEMBL14504237 | 0.86 | BRPF1 (0.59) | CA1CA2CA12CA9BRPF1 | |
| SCHEMBL14503700 | 0.85 | L3MBTL1 (0.54) | CA1CA2CA12CA9 | |
| SCHEMBL14504122 | 0.84 | PTGS2 (0.51) | CA1CA2CA12CA9SMN1; SMN2 | |
| SCHEMBL5396837 | 0.84 | CA1 (0.43) | CA1CA2CA12CA9AKT1 | |
| SCHEMBL14504496 | 0.83 | BRPF1 (0.45) | CA1CA2CA12CA9BRPF1 | |
| SCHEMBL14505190 | 0.83 | PTGS2 (0.51) | CA1CA2CA12CA9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |