Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.44 |
| ▸ | RXRB | P28702 | 3/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10071953 | 0.86 | RXRA (0.41) | RXRARXRBRXRGERN1POLB | |
| SCHEMBL21101846 | 0.83 | KIF11 (0.40) | RXRARXRBRXRGMAPTKDM4E | |
| SCHEMBL5961752 | 0.77 | TSHR (0.36) | RXRARXRBRXRGFFAR1MAPT | |
| SCHEMBL15342832 | 0.76 | KDM4E (0.32) | RXRAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL17127349 | 0.76 | NQO1 (0.56) | ERN1POLBMAPTKDM4EL3MBTL1 | |
| SCHEMBL12731097 | 0.75 | MAPT (0.45) | RXRARXRBPOLBMAPTLMNA | |
| SCHEMBL14507240 | 0.74 | KMT2A (0.47) | RXRARXRBPOLBMAPTLMNA | |
| SCHEMBL21004096 | 0.74 | ELANE (0.44) | RXRARXRBRXRGERN1POLB | |
| SCHEMBL15339088 | 0.73 | ELANE (0.36) | RXRAPOLBMAPTKDM4EL3MBTL1 | |
| SCHEMBL15342844 | 0.73 | GAPDH (0.33) | MAPTKDM4EMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070134447-A1 | Lateral a-substituted acrylate compound and polymer thereof | CHISSO CORPORATION | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070134447-A1 | Lateral a-substituted acrylate compound and polymer thereof | AFF1, CNKSR1, LEF1 | RXRA 668/4885RXRB 1297/4885RXRG 1914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.