Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14534351 | 0.79 | MGAM (0.46) | LMNATSHRCRBNMAPT | |
| SCHEMBL2792579 | 0.79 | LMNA (0.43) | LMNATSHRMAPTALDH1A1CYP2D6 | |
| SCHEMBL229792 | 0.78 | TSHR (0.50) | LMNATSHRMAPTALDH1A1CYP2D6 | |
| SCHEMBL6955795 | 0.77 | LMNA (0.42) | LMNATSHRMAPTALDH1A1CYP2D6 | |
| SCHEMBL28727541 | 0.76 | LMNA (0.48) | LMNATSHRMAPTALDH1A1CYP2D6 | |
| SCHEMBL28875912 | 0.76 | LMNA (0.48) | LMNATSHRMAPTALDH1A1CYP2D6 | |
| SCHEMBL18152012 | 0.76 | LMNA (0.48) | LMNATSHRMAPTALDH1A1CYP2D6 | |
| SCHEMBL28315849 | 0.76 | LMNA (0.48) | LMNATSHRMAPTALDH1A1CYP2D6 | |
| SCHEMBL10900554 | 0.76 | LMNA (0.41) | LMNATSHRMAPTALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7273082 | 0.74 | LMNA (0.39) | LMNATSHRMAPTALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070108405-A1 | Compositions and methods for delivery of biologically active agents | FH FAULDING & CO., LTD. (AU) | 2007-05-17 | — | — | US | disclosed |