Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229792 | 0.84 | TSHR (0.50) | LMNATSHRMAPTCYP2D6ALDH1A1 | |
| SCHEMBL28315849 | 0.81 | LMNA (0.48) | LMNATSHRMAPTCYP2D6ALDH1A1 | |
| SCHEMBL18152012 | 0.81 | LMNA (0.48) | LMNATSHRMAPTCYP2D6ALDH1A1 | |
| SCHEMBL28875912 | 0.81 | LMNA (0.48) | LMNATSHRMAPTCYP2D6ALDH1A1 | |
| SCHEMBL28727541 | 0.81 | LMNA (0.48) | LMNATSHRMAPTCYP2D6ALDH1A1 | |
| SCHEMBL10900554 | 0.81 | LMNA (0.41) | LMNATSHRMAPTCHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL7273082 | 0.79 | LMNA (0.39) | LMNATSHRMAPTCHRM2CHRM4 | |
| SCHEMBL21077405 | 0.79 | FAAH (0.39) | LMNATSHRMAPTCHRM2CHRM4 | |
| SCHEMBL14508455 | 0.79 | LMNA (0.39) | LMNATSHRMAPTCHRM2CHRM4 | |
| SCHEMBL1012855 | 0.79 | LMNA (0.46) | LMNATSHRMAPTCYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100163070-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBRES USING HEATING MEANS AND AN AMIDE | L'OREAL S.A. (FR) | 2010-07-01 | — | — | US | claimed |
| US-11399611-B2 | Process for straightening keratin fibres with a heating means and denaturing agents | L'OREAL (FR) | 2022-08-02 | — | — | US | disclosed |
| US-20190125051-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L'OREAL (FR) | 2019-05-02 | — | — | US | disclosed |
| US-10092490-B2 | Method for straightening keratinous fibres using heating means and an amide | L'OREAL (FR) | 2018-10-09 | — | — | US | disclosed |
| US-20140326268-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L'OREAL (FR) | 2014-11-06 | — | — | US | disclosed |
| US-8765107-B2 | Process for straightening keratin fibres with a heating means and denaturing agents | L'OREAL (FR) | 2014-07-01 | — | — | US | disclosed |
| US-20120192888-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L 'Oréal S.A., (FR) | 2012-08-02 | — | — | US | disclosed |
| US-20100163070-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBRES USING HEATING MEANS AND AN AMIDE | L'OREAL S.A. (FR) | 2010-07-01 | — | — | US | disclosed |
| US-20100028280-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L'OREAL S.A. (FR) | 2010-02-04 | — | — | US | disclosed |
| US-6248571-B1 | USING RHODOCOCCUS TO CONVERT STARTING MATERIAL INTO MALONIC ACID DERVIATIVE, THEN CYCLIZING WITH CARBOXAMIDE IN PRESENCE OF BASE; CHEMICAL INTERMEDIATES FOR INSECTICIDES | LONZA AG (CH) | 2001-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120192888-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | KRT18, KRTCAP2, TUBB4A | LMNA 137/4885TSHR 4635/4885MAPT 90/4885 |
| US-11399611-B2 | Process for straightening keratin fibres with a heating means and denaturing agents | KRT18, KRTCAP2, TUBB4A | LMNA 137/4885TSHR 4635/4885MAPT 90/4885 |
| US-20100028280-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | KRT18, KRTCAP2, TUBB4A | LMNA 137/4885TSHR 4635/4885MAPT 90/4885 |
| US-20190125051-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | KRT18, KRTCAP2, TUBB4A | LMNA 137/4885TSHR 4635/4885MAPT 90/4885 |
| US-10092490-B2 | Method for straightening keratinous fibres using heating means and an amide | KRT18, TUBB3, KIF5C | LMNA 266/4885TSHR 4076/4885MAPT 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.