Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7273082 | 0.98 | LMNA (0.39) | LMNATSHRMAPTF2F10 | |
| SCHEMBL2792579 | 0.81 | LMNA (0.43) | LMNATSHRMAPTCHRM2CHRM4 | |
| SCHEMBL229792 | 0.80 | TSHR (0.50) | LMNATSHRMAPTCYP2D6ALDH1A1 | |
| SCHEMBL11669499 | 0.78 | LMNA (0.39) | LMNAALDH1A1 | |
| SCHEMBL28727541 | 0.78 | LMNA (0.48) | LMNATSHRMAPTCYP2D6ALDH1A1 | |
| SCHEMBL28875912 | 0.78 | LMNA (0.48) | LMNATSHRMAPTCYP2D6ALDH1A1 | |
| SCHEMBL28315849 | 0.78 | LMNA (0.48) | LMNATSHRMAPTCYP2D6ALDH1A1 | |
| SCHEMBL18152012 | 0.78 | LMNA (0.48) | LMNATSHRMAPTCYP2D6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8805713 | 0.77 | LMNA (0.41) | LMNATSHRMAPTCYP2D6ALDH1A1 | |
| SCHEMBL14087042 | 0.77 | NLRP3 (0.40) | LMNATSHRMAPTF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3951990-A | CORONARY AGENTS, HYPOTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | claimed |
| US-8084643-B2 | Nitrogen-containing esters of the secondary alcohol group of florfenicol and of its analogs,including salts; veterinary medicine; nonhydrolyzing as needed to maintain the prodrug in aqueous solution in the subjects system until appropriate; cattle drinking water; bovine respiratory disease | INTERVET INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-8044230-B2 | Hydrolytic stability needed to maintain the prodrug in solution in the subject's system until appropriate conditions exist when the prodrug can hydrolyze, releasing the active compound | INTERVET INC. (US) | 2011-10-25 | — | — | US | disclosed |
| US-20080188556-A1 | Water-Soluble Prodrugs of Florfenicol and its Analogs | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2008-08-07 | — | — | US | disclosed |
| US-20080153906-A1 | Water-Soluble Phenicol Prodrugs in a Lipophilic Vehicle System | INTERVET INC. | 2008-06-26 | — | — | US | disclosed |
| US-20080146640-A1 | Water-Soluble Prodrugs of Chloramphenicol, Thiamphenicol, and Analogs Thereof | SCHERING-PLOUGH LTD. (CH) | 2008-06-19 | — | — | US | disclosed |
| US-4622332-A | Asymmetric diesters of Hantzsch dihydropyridines with hypotensive activity | BAYER AKTIENGESELLSCHAFT (DE) | 1986-11-11 | — | — | US | disclosed |
| US-4049662-A | HYPOTENSIVE AGENTS, VASODILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-20 | — | — | US | disclosed |
| US-4022898-A | ANTIHYPERTENSIVE AGENTS, VASODILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-10 | — | — | US | disclosed |
| US-4016277-A | ANTIHYPERTENSIVE AGENTS AND CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |
| US-3971791-A | VASODILATION, HYPOTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-27 | — | — | US | disclosed |
| US-3959474-A | 2,6-Diamino-1,4-dihydropyridine-3,5-dicarboxylic acid esters used as coronary vessel dilators and anti-hypertensive agents | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-25 | — | — | US | disclosed |
| US-3957998-A | ADMINISTERING | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |
| US-3951990-A | CORONARY AGENTS, HYPOTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3951992-A | CORONARY, HYPOTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3951991-A | CORONARY AGENTS, HYPOTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3950336-A | HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |
| US-3946026-A | HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |
| US-3939171-A | HYPOTENSIVE, VASODILATION | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-17 | — | — | US | disclosed |
| US-3935223-A | 2-Amino-1,4-dihydropyridine derivatives | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153906-A1 | Water-Soluble Phenicol Prodrugs in a Lipophilic Vehicle System | BPHL, CYP4B1, CYP4A22 | LMNA 614/4885TSHR 2907/4885MAPT 1057/4885 |
| US-20080188556-A1 | Water-Soluble Prodrugs of Florfenicol and its Analogs | PFAS, ADH5, SI | LMNA 2524/4885TSHR 3559/4885MAPT 2357/4885 |
| US-20080146640-A1 | Water-Soluble Prodrugs of Chloramphenicol, Thiamphenicol, and Analogs Thereof | TREH, ADH5, CES2 | LMNA 3313/4885TSHR 1911/4885MAPT 2293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.