Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.34 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13397435 | 0.92 | PRMT3 (0.37) | CARM1PRMT1PRMT3PRMT6PRMT8 | |
| SCHEMBL8852143 | 0.83 | SLC6A2 (0.41) | CARM1PRMT1PRMT3PRMT6PRMT8 | |
| SCHEMBL8852142 | 0.83 | PRMT3 (0.31) | CARM1PRMT1PRMT3PRMT6PRMT8 | |
| SCHEMBL13397478 | 0.80 | SIGMAR1 (0.33) | CARM1PRMT1PRMT3PRMT6PRMT8 | |
| SCHEMBL18233628 | 0.78 | — | — | |
| SCHEMBL17914491 | 0.77 | ADH1A (0.45) | ADH1BADH1CADH1A | |
| SCHEMBL14380055 | 0.77 | KMT2A (0.36) | ADH1BADH1CADH1A | |
| SCHEMBL17346064 | 0.75 | ADH1B (0.33) | ADH1BADH1CADH1A | |
| SCHEMBL736236 | 0.75 | ADH1A (0.36) | ADH1BADH1CADH1A | |
| SCHEMBL9927917 | 0.75 | ADH1A (0.41) | ADH1BADH1CADH1ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1795527-A1 | CARBAMOYL-SUBSTITUTED SPIRO DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-06-13 | — | — | EP | disclosed |