Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4977473 | 0.93 | NPC1 (0.51) | NPC1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL4978800 | 0.92 | NPC1 (0.46) | NPC1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL14514279 | 0.88 | MAPT (0.49) | NPC1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL4979511 | 0.87 | NPC1 (0.46) | NPC1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL12802917 | 0.87 | MAPK1 (0.44) | NPC1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL4980859 | 0.86 | LMNA (0.49) | NPC1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL4977185 | 0.86 | L3MBTL1 (0.43) | NPC1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL13030444 | 0.85 | NPC1 (0.77) | NPC1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL14036590 | 0.85 | NPC1 (0.41) | NPC1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL4982121 | 0.85 | NPC1 (0.41) | NPC1MAPTKMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214742-B2 | 2-hydroxyphenyl-s-triazine crosslinkers for polymer networks | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-05-08 | — | — | US | disclosed |
| US-7214742-B2 | 2-hydroxyphenyl-s-triazine crosslinkers for polymer networks | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-05-08 | — | — | US | disclosed |