Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.47 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.47 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14340101 | 0.87 | KCNQ3 (0.57) | FAAHNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14516678 | 0.84 | KCNQ3 (0.51) | FAAHNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28372986 | 0.83 | RAB9A (0.71) | FAAHNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14516681 | 0.83 | KCNQ3 (0.54) | FAAHNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4437426 | 0.83 | MMP2 (0.58) | FAAHNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14516688 | 0.81 | EGLN1 (0.56) | LMNAKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL29518293 | 0.81 | FAAH (0.62) | FAAHNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28372959 | 0.81 | FAAH (0.62) | FAAHNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14516692 | 0.80 | KCNQ3 (0.43) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL29518652 | 0.80 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205307-B2 | Pyrimidines as novel openers of potassium ion channels | ICAGEN, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-7205307-B2 | Pyrimidines as novel openers of potassium ion channels | ICAGEN, INC. (US) | 2007-04-17 | — | — | US | disclosed |