SCHEMBL14517816

C=CCOC(=O)C(N1C(=O)[C@H](C(C)O[Si](C)(C)C(C)(C)C)[C@H]1CC(=O)c1ccc(CO[Si](C)(C)C(C)(C)C)cc1)=P(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	ELANE	P08246	1/20	0.36

▸	FAAH	O00519	2/20	0.32

▸	BTN3A1	O00481	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14517825	0.93	ELANE (0.33)	ELANEFAAH
SCHEMBL13946832	0.93	ELANE (0.34)	ELANEFAAH
SCHEMBL13946840	0.93	ELANE (0.34)	ELANEFAAH
SCHEMBL14517808	0.92	ELANE (0.37)	ELANEFAAH
SCHEMBL5427057	0.92	ELANE (0.33)	ELANEFAAH
SCHEMBL4510767	0.92	FAAH (0.33)	ELANEFAAH
SCHEMBL14517824	0.91	ELANE (0.34)	ELANEFAAH
SCHEMBL14517827	0.91	ELANE (0.32)	ELANEFAAH
SCHEMBL14517846	0.91	ELANE (0.32)	ELANEFAAH
SCHEMBL14517826	0.90	ELANE (0.31)	ELANEFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7205291-B2	High mouth absorption; antibiotics against gramnegative, grampositive bacteria espscially Staphlococcus pneumonia, Hemophilus influenza	DAINIPPON SUMITOMO PHARMA CO., LTD. (JP)	2007-04-17	—	—	US	disclosed