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SCHEMBL14517827

SCHEMBL14517827

C=CCOC(=O)C(N1C(=O)[C@H](C(C)O[Si](C)(C)C(C)(C)C)[C@H]1CC(=O)c1ccc(CC(N)=O)cc1)=P(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 1/20 0.32
▸ FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5427057 0.94 ELANE (0.33) ELANEFAAH
SCHEMBL13946832 0.92 ELANE (0.34) ELANEFAAH
SCHEMBL14517824 0.92 ELANE (0.34) ELANEFAAH
SCHEMBL14517826 0.92 ELANE (0.31) ELANEFAAH
SCHEMBL14517846 0.92 ELANE (0.32) ELANEFAAH
SCHEMBL14517816 0.91 ELANE (0.36) ELANEFAAH
SCHEMBL4510767 0.91 FAAH (0.33) ELANEFAAH
SCHEMBL13946840 0.91 ELANE (0.34) ELANEFAAH
SCHEMBL14517825 0.90 ELANE (0.33) ELANEFAAH
SCHEMBL5433085 0.89 ELANE (0.32) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7205291-B2 High mouth absorption; antibiotics against gramnegative, grampositive bacteria espscially Staphlococcus pneumonia, Hemophilus influenza DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2007-04-17 — — US disclosed
US-7205291-B2 High mouth absorption; antibiotics against gramnegative, grampositive bacteria espscially Staphlococcus pneumonia, Hemophilus influenza DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2007-04-17 — — US disclosed