SCHEMBL4510767

SCHEMBL4510767

C=CCOC(=O)C(N1C(=O)[C@H]([C@@H](C)O[Si](C)(C)C(C)(C)C)[C@H]1CC(=O)c1ccc(CCO)cc1)=P(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.33
ELANE P08246 1/20 0.32
MGLL Q99685 1/20 0.32
CASP1 P29466 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13946832 0.94 ELANE (0.34) FAAHELANEMGLL
SCHEMBL14517825 0.93 ELANE (0.33) FAAHELANEMGLL
SCHEMBL13946799 0.92 FAAH (0.32) FAAHELANECASP1
SCHEMBL5427057 0.92 ELANE (0.33) FAAHELANEMGLLCASP1
SCHEMBL14517816 0.92 ELANE (0.36) FAAHELANE
SCHEMBL14517824 0.91 ELANE (0.34) FAAHELANE
SCHEMBL13946840 0.91 ELANE (0.34) FAAHELANE
SCHEMBL14517827 0.91 ELANE (0.32) FAAHELANE
SCHEMBL14517846 0.91 ELANE (0.32) FAAHELANE
SCHEMBL14543064 0.91 FAAH (0.33) FAAHELANEMGLLCASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090029964-A1 Novel carbapenem compound DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2009-01-29 US disclosed
US-7205291-B2 High mouth absorption; antibiotics against gramnegative, grampositive bacteria espscially Staphlococcus pneumonia, Hemophilus influenza DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2007-04-17 US disclosed
US-7205291-B2 High mouth absorption; antibiotics against gramnegative, grampositive bacteria espscially Staphlococcus pneumonia, Hemophilus influenza DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2007-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090029964-A1 Novel carbapenem compound MGAM2, OXA1L, RIOX2 FAAH 4035/4885ELANE 978/4885MGLL 2333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.