Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 15/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 14/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5352053 | 0.76 | ACHE (0.47) | MTNR1BMTNR1ACES2CES1 | |
| SCHEMBL14518797 | 0.74 | HSD17B2 (0.57) | MTNR1BMTNR1A | |
| SCHEMBL29940269 | 0.74 | HSD17B2 (0.57) | MTNR1BMTNR1A | |
| SCHEMBL31319104 | 0.71 | MTNR1A (0.47) | MTNR1BMTNR1ACES2CES1 | |
| SCHEMBL15831230 | 0.71 | MEN1 (0.62) | — | |
| SCHEMBL8384852 | 0.70 | MTNR1A (0.45) | MTNR1BMTNR1ACES2CES1 | |
| SCHEMBL28470846 | 0.69 | MTNR1A (0.55) | MTNR1BMTNR1ACES2CES1 | |
| SCHEMBL6962874 | 0.69 | MTNR1A (0.56) | MTNR1BMTNR1ACES2CES1 | |
| SCHEMBL5304699 | 0.69 | MTNR1A (0.56) | MTNR1BMTNR1ACES2CES1 | |
| SCHEMBL11658674 | 0.69 | MTNR1A (0.56) | MTNR1BMTNR1ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070082908-A1 | Bicycle pyrazole derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082908-A1 | Bicycle pyrazole derivative | DPP4, DPP7, DPP3 | MTNR1B 1836/4885MTNR1A 2022/4885CES2 436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.