Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | FOS | P01100 | 1/20 | 0.45 |
| ▸ | JUN | P05412 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14518797 | 0.73 | HSD17B2 (0.57) | MTNR1AMTNR1B | |
| SCHEMBL29940269 | 0.73 | HSD17B2 (0.57) | MTNR1AMTNR1B | |
| SCHEMBL2622487 | 0.72 | MAOB (0.62) | MAOBFOSJUNBCHERELA | |
| SCHEMBL16160151 | 0.71 | MEN1 (0.54) | MTNR1AMTNR1BMAOBMEN1ALDH1A1 | |
| SCHEMBL4861174 | 0.71 | ALDH1A1 (0.61) | MAOBMEN1ALDH1A1KMT2AFOS | |
| SCHEMBL23188 | 0.70 | NPC1 (0.65) | MAOBALDH1A1CHRM5RELAMAOA | |
| SCHEMBL29399968 | 0.70 | NPC1 (0.65) | MAOBALDH1A1CHRM5RELAMAOA | |
| SCHEMBL7684603 | 0.70 | NPC1 (0.65) | MAOBALDH1A1CHRM5RELAMAOA | |
| SCHEMBL8384857 | 0.70 | MEN1 (0.51) | MEN1ALDH1A1KMT2ABCHEHPGD | |
| SCHEMBL15831230 | 0.70 | MEN1 (0.62) | MAOBMEN1ALDH1A1KMT2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977132-A | GALACTORRHEA, HYPERPROLACTINEMIC OVULATION, PROLACTINOMA AND BRAIN TUMORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-02 | — | — | US | disclosed |