Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | PLAU | P00749 | 1/20 | 0.61 |
| ▸ | HPN | P05981 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 6/20 | 0.49 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP13 | P45452 | 2/20 | 0.49 |
| ▸ | MMP7 | P09237 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14544528 | 0.87 | ALDH1A1 (0.67) | ALDH1A1PLAUHPNCYP1A2CYP2C9 | |
| SCHEMBL15213296 | 0.87 | MMP9 (0.63) | ALDH1A1MMP9POLBTDP1GAA | |
| SCHEMBL14519991 | 0.87 | MMP9 (0.63) | ALDH1A1MMP9POLBTDP1GAA | |
| SCHEMBL28579685 | 0.79 | ALDH1A1 (0.57) | ALDH1A1PLAUHPNCYP1A2CYP2C9 | |
| SCHEMBL28615849 | 0.79 | ALDH1A1 (0.75) | ALDH1A1PLAUHPNCYP1A2CYP2C9 | |
| SCHEMBL8146180 | 0.78 | ALDH1A1 (0.63) | ALDH1A1CYP1A2CYP2C9CYP2C19MMP9 | |
| SCHEMBL8146178 | 0.78 | ALDH1A1 (0.63) | ALDH1A1CYP1A2CYP2C9CYP2C19MMP9 | |
| SCHEMBL8707457 | 0.78 | ALDH1A1 (0.63) | ALDH1A1CYP1A2CYP2C9CYP2C19MMP9 | |
| SCHEMBL18649638 | 0.78 | MMP2 (0.75) | ALDH1A1MMP9POLBMMP2MMP3 | |
| SCHEMBL697476 | 0.78 | MMP2 (0.79) | ALDH1A1MMP9POLBTDP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | PHARMACIA CORPORATION | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | MAPK1, MAPK3, MAPK4 | ALDH1A1 1079/4885PLAU 2990/4885HPN 4157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.