Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 9/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MMP2 | P08253 | 9/20 | 0.61 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.55 |
| ▸ | MMP7 | P09237 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15213296 | 1.00 | MMP9 (0.63) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL18649638 | 0.91 | MMP2 (0.75) | MMP9MMP2ADAMTS4ALDH1A1MAPT | |
| SCHEMBL8018411 | 0.88 | MMP9 (0.61) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL697476 | 0.88 | MMP2 (0.79) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL697477 | 0.88 | MMP2 (0.79) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL1203540 | 0.88 | MMP2 (0.79) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL5481551 | 0.87 | MMP9 (0.60) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL617758 | 0.87 | MMP9 (0.60) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL14519844 | 0.87 | ALDH1A1 (0.68) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3839410 | 0.86 | MMP2 (0.77) | MMP9TDP1MMP2ADAMTS4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230045142-A1 | SMALL MOLECULE RPN13 INHIBITORS WITH ANTITUMOR PROPERTIES | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-02-09 | — | — | US | disclosed |
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | PHARMACIA CORPORATION | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | MAPK1, MAPK3, MAPK4 | MMP9 1977/4885TDP1 1869/4885MMP2 487/4885 |
| US-20230045142-A1 | SMALL MOLECULE RPN13 INHIBITORS WITH ANTITUMOR PROPERTIES | MRPS23, RPP30, RPS19 | MMP9 2097/4885TDP1 2524/4885MMP2 2364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.