Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927269 | 0.90 | MEN1 (0.70) | KMT2AMEN1TDP1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL27088452 | 0.84 | KMT2A (0.75) | KMT2AMEN1TDP1ALDH1A1HPGD | |
| SCHEMBL4548026 | 0.82 | L3MBTL1 (0.71) | KMT2AMEN1TDP1ALDH1A1LMNA | |
| SCHEMBL6043600 | 0.82 | GNAI3 (0.50) | KMT2AMEN1TDP1ALDH1A1HPGD | |
| SCHEMBL12923889 | 0.82 | PAOX (0.61) | KMT2AMEN1TDP1ALDH1A1HPGD | |
| SCHEMBL6043595 | 0.82 | GNAI3 (0.50) | KMT2AMEN1TDP1ALDH1A1HPGD | |
| SCHEMBL5313045 | 0.82 | LMNA (0.59) | KMT2AMEN1TDP1ALDH1A1HPGD | |
| SCHEMBL4865397 | 0.82 | ATM (0.71) | KMT2AMEN1TDP1ALDH1A1HPGD | |
| SCHEMBL8972071 | 0.81 | GNAI3 (0.71) | KMT2AMEN1TDP1GNAI3GNAI1 | |
| SCHEMBL8212451 | 0.81 | GNAI3 (0.49) | KMT2AMEN1TDP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070088043-A1 | Novel HDAC inhibitors | ORCHID RESEARCH LABORATORIES LIMITED. (IN) | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088043-A1 | Novel HDAC inhibitors | HDAC1, HDAC11, HDAC5 | KMT2A 168/4885MEN1 4128/4885TDP1 813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.