Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12038457 | 1.00 | CHRM5 (0.35) | CHRM5CHRM3HSD17B10SIGMAR1TSHR | |
| SCHEMBL12231841 | 0.99 | CHRM5 (0.34) | CHRM5CHRM3HSD17B10SIGMAR1TSHR | |
| SCHEMBL1241407 | 0.93 | CHRM5 (0.39) | CHRM5CHRM3SIGMAR1EGFR | |
| SCHEMBL29673006 | 0.91 | CHRM5 (0.38) | CHRM5CHRM3SIGMAR1EGFR | |
| SCHEMBL560792 | 0.91 | HSD17B10 (0.39) | HSD17B10TSHRSLC6A9 | |
| SCHEMBL15518427 | 0.91 | HSD17B10 (0.39) | HSD17B10TSHRSLC6A9 | |
| SCHEMBL6666931 | 0.89 | SLC6A9 (0.33) | CHRM5CHRM3SLC6A9 | |
| SCHEMBL17057486 | 0.87 | HSD17B10 (0.36) | CHRM5CHRM3HSD17B10TSHRSLC6A9 | |
| SCHEMBL17053358 | 0.87 | HSD17B10 (0.36) | CHRM5CHRM3HSD17B10TSHRSLC6A9 | |
| SCHEMBL25518167 | 0.84 | HSD17B10 (0.32) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007064759-A2 | INHIBITING TUMOUR CELL INVASION, METASTASIS AND ANGIOGENESIS THROUGH TARGETTING LEGUMAIN | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-06-07 | — | — | WO | disclosed |