SCHEMBL15518427

SCHEMBL15518427

O=C(O)CN1CCN(CC(=O)O)CCN(CC(=O)ON2C(=O)CCC2=O)CC1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 1/20 0.39
▸ SLC6A9 P48067 1/20 0.36
▸ MGLL Q99685 3/20 0.33
▸ TSHR P16473 1/20 0.33
▸ S1PR1 P21453 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ CHRNB2 P17787 1/20 0.31
▸ CHRNB4 P30926 1/20 0.31
▸ CHRNA3 P32297 1/20 0.31
▸ CHRNA4 P43681 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ GSK3A P49840 1/20 0.31
▸ GSK3B P49841 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ TGM2 P21980 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL560792 1.00 HSD17B10 (0.39) HSD17B10SLC6A9MGLLTSHRS1PR1
SCHEMBL17057486 0.95 HSD17B10 (0.36) HSD17B10SLC6A9MGLLTSHRS1PR1
SCHEMBL17053358 0.95 HSD17B10 (0.36) HSD17B10SLC6A9MGLLTSHRS1PR1
SCHEMBL12238070 0.92 LMNA (0.36) HSD17B10TSHRALDH1A1SMN1; SMN2MEN1
SCHEMBL437100 0.92 LMNA (0.36) HSD17B10TSHRALDH1A1SMN1; SMN2MEN1
SCHEMBL12038457 0.91 CHRM5 (0.35) HSD17B10SLC6A9TSHR
SCHEMBL14522328 0.91 CHRM5 (0.35) HSD17B10SLC6A9TSHR
SCHEMBL25039379 0.90 HSD17B10 (0.33) HSD17B10SLC6A9
SCHEMBL23662688 0.90 SLC6A9 (0.33) HSD17B10SLC6A9TSHR
SCHEMBL12231841 0.90 CHRM5 (0.34) HSD17B10SLC6A9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118490641-A Preparation method and application of macromolecular metal beta-lactamase inhibitor 山西省人民医院 2024-08-16 — — CN claimed
CN-117924427-A Al (aluminum) alloy18F-labeled antibacterial peptide UBI 29-41 derivative and preparation method and application thereof 北京师范大学 2024-04-26 — — CN claimed
CN-117653755-A Tumor diagnosis molecular imaging probe based on amino acid metabolic pathway and preparation method and application thereof 中国人民解放军海军军医大学第一附属医院 2024-03-08 — — CN claimed
CN-117338961-A PD-L1 targeting molecular probe and preparation method and application thereof 江南大学 2024-01-05 — — CN claimed
CN-114044804-A TMTP1 polypeptide ligand radioactive probe and preparation method and application thereof 厦门大学附属第一医院 2022-02-15 — — CN claimed
EP-4211146-B1 SYNTHETIC CYCLIC PEPTIDE MIMETICS UNIV BAR ILAN (IL) 2026-05-20 — — EP disclosed
US-12616760-B2 Synthetic cyclic peptide mimetics BAR ILAN UNIVERSITY (IL) 2026-05-05 — — US disclosed
US-20260055182-A1 ANTI-L1-CAM ANTIBODIES AND THEIR USES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS CIS BIOPHARMA AG (CH) 2026-02-26 — — US disclosed
US-12551583-B2 Radiolabeled ligands for targeted PET/SPECT imaging and methods of their use MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2026-02-17 — — US disclosed
US-20260007787-A1 RADIOPHARMACEUTICAL SMALL MOLECULE INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED THERAPY AND DIAGNOSTIC IMAGING OF DESMOPLASTIC TUMORS TRUSTEES OF TUFTS COLLEGE 2026-01-08 — — US disclosed
WO-2025238187-A1 IMMUNOCONJUGATES TARGETING L1-CAM CIS BIOPHARMA AG (CH) 2025-11-20 — — WO disclosed
US-20250339569-A1 CARBONIC ANHYDRASE IX LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2025-11-06 — — US disclosed
WO-2015121092-A1 OPIOID RECEPTOR BINDING AGENTS AND USES THEREOF VIB VZW (BE) 2015-08-20 — — WO disclosed
WO-2015073678-A1 COMPOUNDS FOR POSITRON EMISSION TOMOGRAPHY ENDOCYTE, INC. (US) 2015-05-21 — — WO disclosed
WO-2015073678-A1 COMPOUNDS FOR POSITRON EMISSION TOMOGRAPHY ENDOCYTE, INC. (US) 2015-05-21 — — WO disclosed
EP-2855526-A1 ANTI-MACROPHAGE MANNOSE RECEPTOR SINGLE VARIABLE DOMAINS FOR TARGETING AND IN VIVO IMAGING OF TUMOR-ASSOCIATED MACROPHAGES VIB vzw (BE) 2015-04-08 — — EP disclosed
US-20150093336-A1 ANTI-MACROPHAGE MANNOSE RECEPTOR SINGLE VARIABLE DOMAINS FOR TARGETING AND IN VIVO IMAGING OF TUMOR-ASSOCIATED MACROPHAGES VRIJE UNIVERSITEIT BRUSSEL (BE) 2015-04-02 — — US disclosed
WO-2014140376-A1 ANTI-MACROPHAGE MANNOSE RECEPTOR SINGLE VARIABLE DOMAINS FOR USE IN CARDIOVASCULAR DISEASES VIB VZW (BE) 2014-09-18 — — WO disclosed
WO-2014037419-A1 IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS DIRECTED AGAINST CD74 AND USES DERIVED THEREOF VIB VZW (BE) 2014-03-13 — — WO disclosed
WO-2013174537-A1 ANTI-MACROPHAGE MANNOSE RECEPTOR SINGLE VARIABLE DOMAINS FOR TARGETING AND IN VIVO IMAGING OF TUMOR-ASSOCIATED MACROPHAGES VIB VZW (BE) 2013-11-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007787-A1 RADIOPHARMACEUTICAL SMALL MOLECULE INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED THERAPY AND DIAGNOSTIC IMAGING OF DESMOPLASTIC TUMORS FIBP, FRS2, FGFR1 HSD17B10 2311/4885SLC6A9 3901/4885MGLL 3372/4885
US-12616760-B2 Synthetic cyclic peptide mimetics TPX2, IAPP, HAX1 HSD17B10 4795/4885SLC6A9 2877/4885MGLL 3692/4885
US-20260055182-A1 ANTI-L1-CAM ANTIBODIES AND THEIR USES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS IGSF11, L1CAM, CD74 HSD17B10 4344/4885SLC6A9 4742/4885MGLL 4619/4885
US-12551583-B2 Radiolabeled ligands for targeted PET/SPECT imaging and methods of their use SLC7A1, SLC38A7, SLC34A2 HSD17B10 4769/4885SLC6A9 144/4885MGLL 1489/4885
US-20250339569-A1 CARBONIC ANHYDRASE IX LIGANDS CA9, CA13, CA4 HSD17B10 3729/4885SLC6A9 1379/4885MGLL 4656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback