SCHEMBL560792

SCHEMBL560792

O=C(O)CN1CCN(CC(=O)O)CCN(CC(=O)ON2C(=O)CCC2=O)CCN(CC(=O)O)CC1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 1/20 0.39
▸ SLC6A9 P48067 1/20 0.36
▸ MGLL Q99685 3/20 0.33
▸ TSHR P16473 1/20 0.33
▸ S1PR1 P21453 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ CHRNB2 P17787 1/20 0.31
▸ CHRNB4 P30926 1/20 0.31
▸ CHRNA3 P32297 1/20 0.31
▸ CHRNA4 P43681 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ GSK3A P49840 1/20 0.31
▸ GSK3B P49841 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ TGM2 P21980 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15518427 1.00 HSD17B10 (0.39) HSD17B10SLC6A9MGLLTSHRS1PR1
SCHEMBL17057486 0.95 HSD17B10 (0.36) HSD17B10SLC6A9MGLLTSHRS1PR1
SCHEMBL17053358 0.95 HSD17B10 (0.36) HSD17B10SLC6A9MGLLTSHRS1PR1
SCHEMBL12238070 0.92 LMNA (0.36) HSD17B10TSHRALDH1A1SMN1; SMN2MEN1
SCHEMBL437100 0.92 LMNA (0.36) HSD17B10TSHRALDH1A1SMN1; SMN2MEN1
SCHEMBL12038457 0.91 CHRM5 (0.35) HSD17B10SLC6A9TSHR
SCHEMBL14522328 0.91 CHRM5 (0.35) HSD17B10SLC6A9TSHR
SCHEMBL25039379 0.90 HSD17B10 (0.33) HSD17B10SLC6A9
SCHEMBL23662688 0.90 SLC6A9 (0.33) HSD17B10SLC6A9TSHR
SCHEMBL12231841 0.90 CHRM5 (0.34) HSD17B10SLC6A9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1059 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260077071-A1 Targeted Delivery of Theranostic Agents PETER MACCALLUM CANCER INST (AU) 2026-03-19 — — US claimed
CN-119954902-A PD-L1 targeted compound HF12, and preparation method and application thereof 中山大学附属第一医院 2025-05-09 — — CN claimed
US-20250127938-A1 THERAGNOSTIC FOLATE CONJUGATES MERCK PATENT GMBH (DE) 2025-04-24 — — US claimed
CN-119798325-A Radiolabel, precursor compound thereof, preparation method and application 西南医科大学附属医院 2025-04-11 — — CN claimed
US-20250108138-A1 THERAGNOSTIC FOLATE CONJUGATES MERCK PATENT GMBH (DE) 2025-04-03 — — US claimed
WO-2025040588-A1 MONOCLONAL ANTI-PTK7 ANTIBODIES AND DERIVATIVES ONCOINVENT AS (NO) 2025-02-27 — — WO claimed
US-12194109-B2 Radioactive compound for treatment of melanoma and use thereof INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) 2025-01-14 — — US claimed
US-20240415989-A1 RADIOLABELED COMPOUND, AND PRECURSOR COMPOUND THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF THE AFFILIATED HOSPITAL OF SOUTHWEST MEDICAL UNIVERSITY (CN) 2024-12-19 — — US claimed
EP-4472677-A1 THERAGNOSTIC FOLATE CONJUGATES Merck Patent GmbH (DE) 2024-12-11 — — EP claimed
EP-4472676-A1 THERAGNOSTIC FOLATE CONJUGATES Merck Patent GmbH (DE) 2024-12-11 — — EP claimed
WO-2022232124-A1 TARGETED ALPHA PARTICLE THERAPY FOR SOMATOSTATIN RECEPTOR 2 POSITIVE NEUROENDOCRINE TUMORS AND METASTASES H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) 2022-11-03 — — WO claimed
CN-114230610-A Radiolabel, precursor compound thereof, preparation method and application 西南医科大学附属医院 2022-03-25 — — CN claimed
US-20220031873-A1 Multi-Modal Contrast Agent For Medical Imaging BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2022-02-03 — — US claimed
US-10973925-B2 Methods and compositions for theranostic nanoparticles UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION INC. (US) 2021-04-13 — — US claimed
EP-3474879-A1 COMPOSITIONS AND METHODS OF TREATING MELANOMA University of Iowa Research Foundation (US) 2019-05-01 — — EP claimed
US-10011587-B2 Multivalent ligands targeting VEGFR THE METHODIST HOSPITAL SYSTEM (US) 2018-07-03 — — US claimed
WO-2017223565-A1 COMPOSITIONS AND METHODS OF TREATING MELANOMA UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2017-12-28 — — WO claimed
WO-2017176216-A1 A MULTIMODAL FLUORESCENT PROBE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-10-12 — — WO claimed
US-9603954-B2 Methods for generating radioimmunoconjugates ACTINIUM PHARMACEUTICALS INC. (US) 2017-03-28 — — US claimed
US-20120220754-A1 METHODS FOR GENERATING RADIOIMMUNOCONJUGATES ACTINIUM PHARMACEUTICALS INC. (US) 2012-08-30 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250108138-A1 THERAGNOSTIC FOLATE CONJUGATES FOLR1, MTHFD1, MTHFD2 HSD17B10 1876/4885SLC6A9 1460/4885MGLL 3992/4885
US-12194109-B2 Radioactive compound for treatment of melanoma and use thereof CD47, TYR, NRAS HSD17B10 4685/4885SLC6A9 4810/4885MGLL 1905/4885
US-20250127938-A1 THERAGNOSTIC FOLATE CONJUGATES FOLR1, FOLR2, DHFR HSD17B10 3985/4885SLC6A9 1595/4885MGLL 4286/4885
US-20240415989-A1 RADIOLABELED COMPOUND, AND PRECURSOR COMPOUND THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF TMEM14C, FURIN, SLC7A1 HSD17B10 4346/4885SLC6A9 609/4885MGLL 2002/4885
US-20260077071-A1 Targeted Delivery of Theranostic Agents CCKAR, NPY1R, NPY2R HSD17B10 2752/4885SLC6A9 191/4885MGLL 660/4885
US-10011587-B2 Multivalent ligands targeting VEGFR KDR, FLT4, FLT1 HSD17B10 4837/4885SLC6A9 4607/4885MGLL 2839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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