Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 9/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TGM1 | P22735 | 1/20 | 0.40 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | TEC | P42680 | 1/20 | 0.36 |
| ▸ | TXK | P42681 | 1/20 | 0.36 |
| ▸ | BMX | P51813 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14690416 | 0.86 | TGM2 (0.53) | TGM2PTPN1PTPN11F13A1LMNA | |
| SCHEMBL13074221 | 0.84 | TGM2 (0.52) | TGM2PTPN1PTPN11F13A1LMNA | |
| SCHEMBL31228347 | 0.81 | TGM2 (0.65) | TGM2PTPN1PTPN11F13A1LMNA | |
| SCHEMBL613090 | 0.81 | TGM2 (0.65) | TGM2PTPN1PTPN11F13A1LMNA | |
| SCHEMBL9702270 | 0.80 | TGM2 (0.47) | TGM2PTPN1PTPN11F13A1LMNA | |
| SCHEMBL5183351 | 0.79 | TGM2 (0.50) | TGM2PTPN1PTPN11LMNAEGFR | |
| SCHEMBL11883844 | 0.77 | TGM2 (0.55) | TGM2PTPN1PTPN11F13A1LMNA | |
| SCHEMBL8243220 | 0.77 | NPC1 (0.36) | KDM4EMAPT | |
| SCHEMBL14690089 | 0.75 | TGM2 (0.54) | TGM2PTPN1PTPN11F13A1LMNA | |
| SCHEMBL2761954 | 0.74 | TGM2 (0.62) | TGM2PTPN1PTPN11F13A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007072521-A1 | POLYMER STRUCTURE REACTING WITH KERATIN, SYNTHESIS AND USE THEREOF | EUDERMIC S.R.L. (IT) | 2007-06-28 | — | — | WO | disclosed |