SCHEMBL31228347

SCHEMBL31228347

C=CC(=O)Nc1ccccc1NC(=O)C=C

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 9/20 0.65
PTPN1 P18031 1/20 0.56
PTPN11 Q06124 1/20 0.56
F13A1 P00488 1/20 0.50
LMNA P02545 1/20 0.50
TGM1 P22735 1/20 0.50
TGM3 Q08188 1/20 0.50
KDM4E B2RXH2 1/20 0.47
MAPT P10636 1/20 0.47
PKM P14618 1/20 0.47
ALDH1A1 P00352 2/20 0.46
RECQL P46063 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
EGFR P00533 1/20 0.46
BTK Q06187 1/20 0.46
GSTO1 P78417 2/20 0.45
MAPK3 P27361 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL613090 1.00 TGM2 (0.65) TGM2PTPN1PTPN11F13A1LMNA
SCHEMBL2761954 0.92 TGM2 (0.62) TGM2PTPN1PTPN11F13A1LMNA
SCHEMBL17524758 0.90 TGM2 (0.55) TGM2PTPN1PTPN11F13A1LMNA
SCHEMBL23653363 0.90 TGM2 (0.55) TGM2PTPN1PTPN11F13A1LMNA
SCHEMBL29366956 0.87 MMP1 (0.59) TGM2PTPN1PTPN11LMNAKDM4E
SCHEMBL17443378 0.87 TGM2 (0.57) TGM2PTPN1PTPN11F13A1LMNA
SCHEMBL9357321 0.87 TGM2 (0.57) TGM2PTPN1PTPN11F13A1LMNA
SCHEMBL413017 0.87 MMP1 (0.59) TGM2PTPN1PTPN11LMNAKDM4E
SCHEMBL1961608 0.87 TGM2 (0.67) TGM2PTPN1PTPN11F13A1LMNA
SCHEMBL11808631 0.86 EGFR (0.60) TGM2PTPN1PTPN11F13A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12618000-B2 Friction reduction of acidic treatment fluids HALLIBURTON ENERGY SERVICES, INC. (US) 2026-05-05 US disclosed
US-20260071533-A1 TREATMENT FLUID SELECTION HALLIBURTON ENERGY SERVICES, INC. (US) 2026-03-12 US disclosed
US-12247165-B2 Anti-syneresis agents for fracturing operations HALLIBURTON ENERGY SERVICES, INC. (US) 2025-03-11 US disclosed
US-20250075122-A1 ADDITIVES TO PREVENT THERMAL THINNING IN POLYMER GEL SYSTEMS HALLIBURTON ENERGY SERVICES, INC. (US) 2025-03-06 US disclosed
US-20250051634-A1 ANTI-SYNERESIS AGENTS FOR FRACTURING OPERATIONS HALLIBURTON ENERGY SERVICES, INC. (US) 2025-02-13 US disclosed
US-20250051635-A1 FRICTION REDUCTION OF ACIDIC TREATMENT FLUIDS HALLIBURTON ENERGY SERVICES, INC. (US) 2025-02-13 US disclosed
WO-2025006003-A1 FRICTION REDUCTION OF ACIDIC TREATMENT FLUIDS HALLIBURTON ENERGY SERVICES, INC. (US) 2025-01-02 WO disclosed
US-20240384227-A1 MATERIALS CHEMISTRIES AND MICROTOPOGRAPHIES AND USES THEREOF THE UNIVERSITY OF NOTTINGHAM (GB) 2024-11-21 US disclosed
US-12139667-B1 Friction reduction of acidic treatment fluids HALLIBURTON ENERGY SERVICES, INC. (US) 2024-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071533-A1 TREATMENT FLUID SELECTION PLG, SOST, CSTB TGM2 3285/4885PTPN1 2490/4885PTPN11 3180/4885
US-12618000-B2 Friction reduction of acidic treatment fluids GFER, FGB, NSF TGM2 3250/4885PTPN1 615/4885PTPN11 972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.