Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | FURIN | P09958 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14524451 | 0.77 | TGM2 (0.50) | KDM4EMAPT | |
| SCHEMBL19380616 | 0.76 | HPGD (0.68) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL14085548 | 0.73 | LMNA (0.45) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8276359 | 0.73 | IDO1 (0.35) | NPC1SMN1; SMN2KMT2AMEN1SIGMAR1 | |
| SCHEMBL23288540 | 0.69 | SIGMAR1 (0.33) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL1270302 | 0.69 | RAB9A (0.69) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL29239839 | 0.69 | NPC1 (0.39) | NPC1RAB9AALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL11791067 | 0.69 | ALDH1A1 (0.48) | NPC1ALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL16980390 | 0.69 | RAB9A (0.69) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL13213707 | 0.69 | GAA (0.58) | ALDH1A1SMN1; SMN2HPGDKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007009109-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2007-01-18 | — | — | WO | disclosed |