SCHEMBL613090

SCHEMBL613090

C=CC(=O)Nc1ccccc1NC(=O)C=C

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 9/20 0.65
PTPN1 P18031 1/20 0.56
PTPN11 Q06124 1/20 0.56
F13A1 P00488 1/20 0.50
LMNA P02545 1/20 0.50
TGM1 P22735 1/20 0.50
TGM3 Q08188 1/20 0.50
KDM4E B2RXH2 1/20 0.47
MAPT P10636 1/20 0.47
PKM P14618 1/20 0.47
ALDH1A1 P00352 2/20 0.46
RECQL P46063 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
EGFR P00533 1/20 0.46
BTK Q06187 1/20 0.46
GSTO1 P78417 2/20 0.45
MAPK3 P27361 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31228347 1.00 TGM2 (0.65) TGM2PTPN1PTPN11F13A1LMNA
SCHEMBL2761954 0.92 TGM2 (0.62) TGM2PTPN1PTPN11F13A1LMNA
SCHEMBL17524758 0.90 TGM2 (0.55) TGM2PTPN1PTPN11F13A1LMNA
SCHEMBL23653363 0.90 TGM2 (0.55) TGM2PTPN1PTPN11F13A1LMNA
SCHEMBL29366956 0.87 MMP1 (0.59) TGM2PTPN1PTPN11LMNAKDM4E
SCHEMBL17443378 0.87 TGM2 (0.57) TGM2PTPN1PTPN11F13A1LMNA
SCHEMBL9357321 0.87 TGM2 (0.57) TGM2PTPN1PTPN11F13A1LMNA
SCHEMBL413017 0.87 MMP1 (0.59) TGM2PTPN1PTPN11LMNAKDM4E
SCHEMBL1961608 0.87 TGM2 (0.67) TGM2PTPN1PTPN11F13A1LMNA
SCHEMBL11808631 0.86 EGFR (0.60) TGM2PTPN1PTPN11F13A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4683969-A1 COATING COMPOSITIONS AND APPLICATIONS THEREOF Aescula Tech, Inc. (US) 2026-01-28 EP claimed
WO-2024196974-A1 COATING COMPOSITIONS AND APPLICATIONS THEREOF AESCULA TECH, INC. (US) 2024-09-26 WO claimed
US-20240315949-A1 COATING COMPOSITIONS AND APPLICATIONS THEREOF AesculaTech, Inc. 2024-09-26 US claimed
EP-2368897-B1 Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays CORNELL RES FOUNDATION INC (US) 2016-10-19 EP claimed
EP-2332958-B1 Detection of nucleic and sequence differences using the ligase detection reaction with addressable arrays CORNELL RES FOUNDATION INC (US) 2016-04-20 EP claimed
EP-1958955-B1 Spatially addressable oligonucleotide arrays and method of making the same CORNELL RES FOUNDATION INC (US) 2013-09-04 EP claimed
EP-0920440-B1 DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS CORNELL RES FOUNDATION INC (US) 2012-08-22 EP claimed
EP-2368897-A1 Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays Cornell Research Foundation, Inc. (US) 2011-09-28 EP claimed
CN-1968970-B Inclusion complexes of unsaturated monomers, their polymers and process for preparation thereof COUNCIL SCIENT IND RES 2011-06-22 CN claimed
EP-2332958-A1 Detection of nucleic and sequence differences using the ligase detection reaction with addressable arrays Cornell Research Foundation, Inc. (US) 2011-06-15 EP claimed
WO-2004095025-A1 IMPROVED COMPOSITE MICROARRY SLIDES CUNO, INC. (US) 2004-11-04 WO claimed
EP-0920440-A4 DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS CORNELL RES FOUNDATION INC (US) 2004-08-25 EP claimed
US-20030219816-A1 Composite microarray slides 3M INNOVATIVE PROPERTIES COMPANY 2003-11-27 US claimed
US-20030148284-A1 Solid phase detection of nucleic acid molecules CORNING INCORPORATED 2003-08-07 US claimed
US-20030022182-A1 Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays CORNELL RESEARCH FOUNDATION, INC. 2003-01-30 US claimed
JP-2001519648-A 2001-10-23 JP claimed
US-6248842-B1 CROSSLINKED POLYMER THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY 2001-06-19 US claimed
US-6177513-B1 Method for evaluating artificial receptors TOSHIFUMI TAKEUCHI (JP) 2001-01-23 US claimed
EP-0920440-A2 DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS CORNELL RESEARCH FOUNDATION, INC. (US) 1999-06-09 EP claimed
WO-1997031256-A2 DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS CORNELL RESEARCH FOUNDATION, INC. (US) 1997-08-28 WO claimed