SCHEMBL14525504

SCHEMBL14525504

Cc1cc(F)c2cc(Cl)ccc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.36
CYP1A2 P05177 3/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
POLB P06746 1/20 0.35
RAPGEF4 Q8WZA2 2/20 0.35
TUBB4A P04350 1/20 0.35
TUBB P07437 1/20 0.35
TUBA3C P0DPH7 1/20 0.35
IDO1 P14902 1/20 0.35
TUBA1B P68363 1/20 0.35
TUBA4A P68366 1/20 0.35
TUBB4B P68371 1/20 0.35
TUBB3 Q13509 1/20 0.35
TUBB2A Q13885 1/20 0.35
TUBB8 Q3ZCM7 1/20 0.35
TUBA3E Q6PEY2 1/20 0.35
TUBA1A Q71U36 1/20 0.35
TUBA1C Q9BQE3 1/20 0.35
TUBB6 Q9BUF5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12227987 0.81 CYP1A2 (0.52) CYP2A6CYP1A2POLBLMNAESR1
SCHEMBL21240955 0.79 CYP2A6 (0.54) CYP2A6CYP1A2MEN1KMT2APOLB
SCHEMBL14525500 0.79 NFE2L2 (0.39) CYP2A6CYP1A2MEN1KMT2ATYMS
SCHEMBL14525495 0.73 RAPGEF4 (0.36) CYP1A2MEN1KMT2ARAPGEF4LMNA
SCHEMBL20047692 0.73 LMNA (0.38) CYP2A6CYP1A2LMNAESR1ESR2
SCHEMBL14525498 0.73 KIF11 (0.46) MEN1KMT2ARAPGEF4
SCHEMBL806448 0.72 CYP1A2 (0.61) CYP2A6CYP1A2MEN1KMT2AALDH1A1
SCHEMBL2723074 0.72 CYP2A6 (0.52) CYP2A6CYP1A2POLBHSP90AB1TYMS
SCHEMBL1248427 0.72 CYP2A6 (0.40) CYP2A6CYP1A2MEN1KMT2APOLB
SCHEMBL27286459 0.72 CYP1A2 (0.46) CYP2A6CYP1A2LMNAESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7198827-B1 Nematic liquid crystal composition and liquid crystal display device using the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-04-03 US disclosed
US-7198827-B1 Nematic liquid crystal composition and liquid crystal display device using the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-04-03 US disclosed