SCHEMBL5080596

SCHEMBL5080596

O=C(c1ccccc1Cl)c1ccc(Cl)cc1Cl

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.71
SMN1; SMN2 Q16637 2/20 0.59
TSHR P16473 1/20 0.59
CASP1 P29466 1/20 0.59
SRD5A2 P31213 1/20 0.56
GABRP O00591 1/20 0.55
GABRD O14764 1/20 0.55
GABRA1 P14867 1/20 0.55
GABRB1 P18505 1/20 0.55
GABRG2 P18507 1/20 0.55
GABRB3 P28472 1/20 0.55
GABRA5 P31644 1/20 0.55
GABRA3 P34903 1/20 0.55
GABRA2 P47869 1/20 0.55
GABRB2 P47870 1/20 0.55
GABRA4 P48169 1/20 0.55
GABRE P78334 1/20 0.55
GABRA6 Q16445 1/20 0.55
GABRG1 Q8N1C3 1/20 0.55
GABRG3 Q99928 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29829303 1.00 RECQL (0.71) RECQLSMN1; SMN2TSHRCASP1SRD5A2
SCHEMBL195020 0.89 SMN1; SMN2 (0.71) RECQLSMN1; SMN2TSHRCASP1SRD5A2
SCHEMBL30185351 0.89 SMN1; SMN2 (0.71) RECQLSMN1; SMN2TSHRCASP1SRD5A2
SCHEMBL11842389 0.88 RECQL (0.77) RECQLGABRPGABRDGABRA1GABRB1
SCHEMBL8864622 0.87 SMN1; SMN2 (0.69) RECQLSMN1; SMN2TSHRCASP1SRD5A2
SCHEMBL9851141 0.86 RECQL (0.74) RECQLGABRPGABRDGABRA1GABRB1
SCHEMBL611947 0.85 RECQL (0.54) RECQLSMN1; SMN2TSHRCASP1SRD5A2
SCHEMBL8296814 0.85 RECQL (0.78) RECQLGABRPGABRDGABRA1GABRB1
SCHEMBL3050631 0.85 RECQL (0.73) RECQLSMN1; SMN2TSHRCASP1SRD5A2
SCHEMBL29399311 0.85 CES2 (0.71) RECQLTSHRGABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552901-B2 Polyarylene sulfide production method KUREHA CORPORATION (JP) 2026-02-17 US disclosed
US-12509555-B2 Method for producing polyarylene sulfide KUREHA CORPORATION (JP) 2025-12-30 US disclosed
US-20230192958-A1 POLYARYLENE SULFIDE PRODUCTION METHOD KUREHA CORPORATION (JP) 2023-06-22 US disclosed
US-20230033026-A1 METHOD FOR PRODUCING POLYARYLENE SULFIDE KUREHA CORPORATION (JP) 2023-02-02 US disclosed
CN-115485320-A Method for producing polyarylene sulfide 株式会社吴羽 2022-12-16 CN disclosed
WO-2021131985-A1 METHOD FOR PRODUCING POLYARYLENE SULFIDE 株式会社クレハ 2021-07-01 WO disclosed
US-10156303-B2 High temperature conduit having a complex, three-dimensional configuration TICONA LLC (US) 2018-12-18 US disclosed
US-10081710-B2 Branched polyarylene sulfide resin, method for manufacturing same and use as polymer modifier KUREHA CORPORATION (JP) 2018-09-25 US disclosed
US-20180044477-A1 BRANCHED POLYARYLENE SULFIDE RESIN, METHOD FOR MANUFACTURING SAME AND USE AS POLYMER MODIFIER KUREHA CORPORATION (JP) 2018-02-15 US disclosed
EP-2655847-B1 FIBER REINFORCED SHAPED ARTICLES AND PROCESS FOR MAKING SAME TICONA LLC (US) 2017-05-31 EP disclosed
WO-2012088375-A2 FIBER REINFORCED SHAPED ARTICLES AND PROCESS FOR MAKING SAME TICONA LLC (US) 2012-06-28 WO disclosed
WO-2012088378-A1 HIGH TEMPERATUE CONDUIT HAVING A COMPLEX, THREE-DIMESNIONAL CONFIGURATION TICONA LLC (US) 2012-06-28 WO disclosed
US-20080004375-A1 Poly (Arylene Sulfide) Resin Composition and Production Process Thereof POLYPLASTICS CO., LTD. (JP) 2008-01-03 US disclosed
EP-1849834-A1 POLYARYLENE SULFIDE RESIN COMPOSITION AND METHOD FOR PRODUCING SAME Polyplastics Co., Ltd. (JP) 2007-10-31 EP disclosed
EP-1837359-A1 BRANCHED POLYARYLENE SULFIDE RESIN, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS POLYMERIC MODIFIER Kureha Corporation (JP) 2007-09-26 EP disclosed
EP-0344977-B1 Process for the preparation of cross-linked polyarylene sulfide KUREHA CHEMICAL IND CO LTD (JP) 1994-10-05 EP disclosed
US-5268451-A Reacting an alkali metal sulfide and a dihaloaromatic compound KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-12-07 US disclosed
US-5200500-A Reacting alkali metal sulfide, dihalo and polyhalo aromatic compounds; high melt viscosity and high crosslinkage KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-04-06 US disclosed
EP-0344977-A2 Process for the preparation of cross-linked polyarylene sulfide KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-12-06 EP disclosed
US-3956324-A THERMOPLASTIC POLYMER CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509555-B2 Method for producing polyarylene sulfide AS3MT, ZW10, POLR2H RECQL 3652/4885SMN1; SMN2 1790/4885TSHR 3498/4885
US-12552901-B2 Polyarylene sulfide production method PEAK1, POLR2H, TDO2 RECQL 3472/4885SMN1; SMN2 1355/4885TSHR 2455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.