SCHEMBL145272

SCHEMBL145272

O=C(OC(=O)C1=CCCc2ccccc21)C1=CCCc2ccccc21

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.39
KDM4E B2RXH2 4/20 0.38
ALDH1A1 P00352 4/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
HPGD P15428 3/20 0.38
MAPT P10636 6/20 0.38
SRD5A1 P18405 1/20 0.38
SRD5A2 P31213 1/20 0.38
MEN1 O00255 1/20 0.38
PLA2G1B P04054 1/20 0.38
KMT2A Q03164 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
LMNA P02545 2/20 0.37
CYP2A6 P11509 1/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5230608 0.86 L3MBTL1 (0.49) CES1KDM4EALDH1A1L3MBTL1HPGD
SCHEMBL8119477 0.83 SRD5A2 (0.49) CES1KDM4EALDH1A1HPGDSRD5A1
SCHEMBL28133174 0.83 CES1 (0.43) CES1KDM4EALDH1A1L3MBTL1HPGD
SCHEMBL13159212 0.82 ALDH1A1 (0.52) KDM4EALDH1A1L3MBTL1HPGDMAPT
SCHEMBL4766870 0.80 CES1 (0.41) CES1KDM4EALDH1A1L3MBTL1HPGD
SCHEMBL6337844 0.80 PTAFR (0.41) CES1ALDH1A1SRD5A1SRD5A2CYP2A6
SCHEMBL8111658 0.80 NOTUM (0.45) CES1KDM4EALDH1A1L3MBTL1HPGD
SCHEMBL2675859 0.76 AKT1 (0.40) CES1KDM4EALDH1A1HPGDMAPT
SCHEMBL26421241 0.76 SMN1; SMN2 (0.49) CES1KDM4EALDH1A1L3MBTL1HPGD
SCHEMBL15237497 0.74 TRPM8 (0.39) CES1KDM4EALDH1A1L3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9647222-B2 Gate insulator layer for organic electronic devices MERCK PATENT GMBH (DE) 2017-05-09 US disclosed
US-9647213-B2 Interlayer for electronic devices MERCK PATENT GMBH (DE) 2017-05-09 US disclosed
US-9583713-B2 Interlayer for electronic devices MERCK PATENT GMBH (DE) 2017-02-28 US disclosed
EP-2676979-B1 Gate insulator layer for electronic devices MERCK PATENT GMBH (DE) 2016-07-13 EP disclosed
US-20150372246-A1 GATE INSULATOR LAYER FOR ORGANIC ELECTRONIC DEVICES FLEXENABLE TECHNOLOGY LIMITED (GB) 2015-12-24 US disclosed
US-20150349263-A1 INTERLAYER FOR ELECTRONIC DEVICES FLEXENABLE TECHNOLOGY LIMITED (GB) 2015-12-03 US disclosed
EP-2611842-B1 INTERLAYER FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-11-04 EP disclosed
US-9175123-B2 Gate insulator layer for organic electronic devices MERCK PATENT GMBH (DE) 2015-11-03 US disclosed
EP-2611841-B1 GATE INSULATOR LAYER FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-10-28 EP disclosed
EP-2676978-B1 INTERLAYER FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-06-24 EP disclosed
EP-2676979-A1 Gate insulator layer for electronic devices Merck Patent GmbH (DE) 2013-12-25 EP disclosed
EP-2676978-A1 Interlayer for electronic devices Merck Patent GmbH (DE) 2013-12-25 EP disclosed
EP-2611841-A1 GATE INSULATOR LAYER FOR ELECTRONIC DEVICES Merck Patent GmbH (DE) 2013-07-10 EP disclosed
EP-2611842-A1 INTERLAYER FOR ELECTRONIC DEVICES Merck Patent GmbH (DE) 2013-07-10 EP disclosed
US-20120056249-A1 INTERLAYER FOR ELECTRONIC DEVICES PROMERUS LLC (US) 2012-03-08 US disclosed
WO-2012028278-A1 INTERLAYER FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-03-08 WO disclosed
WO-2012028279-A1 GATE INSULATOR LAYER FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-03-08 WO disclosed
US-20120056183-A1 GATE INSULATOR LAYER FOR ORGANIC ELECTRONIC DEVICES PROMERUS LLC (US) 2012-03-08 US disclosed
US-4222829-A ACYLATED POLYALKYLENIMINE BRIGHTENER POPESCU FRANCINE 1980-09-16 US disclosed