Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | PTAFR | P25105 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28133174 | 0.88 | CES1 (0.43) | SRD5A2SRD5A1KDM4EALDH1A1NOTUM | |
| SCHEMBL4766870 | 0.85 | CES1 (0.41) | SRD5A2SRD5A1KDM4EALDH1A1NOTUM | |
| SCHEMBL8111658 | 0.85 | NOTUM (0.45) | SRD5A2SRD5A1KDM4EALDH1A1NOTUM | |
| SCHEMBL6337844 | 0.85 | PTAFR (0.41) | SRD5A2SRD5A1ALDH1A1NOTUMCES1 | |
| SCHEMBL145272 | 0.83 | CES1 (0.39) | SRD5A2SRD5A1KDM4EALDH1A1NOTUM | |
| SCHEMBL5230608 | 0.80 | L3MBTL1 (0.49) | KDM4EALDH1A1LMNAHPGDCES1 | |
| SCHEMBL2675859 | 0.80 | AKT1 (0.40) | SRD5A2SRD5A1KDM4EALDH1A1NOTUM | |
| SCHEMBL26421241 | 0.80 | SMN1; SMN2 (0.49) | SRD5A2SRD5A1KDM4EALDH1A1HPGD | |
| SCHEMBL335207 | 0.79 | SRD5A2 (0.43) | SRD5A2SRD5A1KDM4EALDH1A1NOTUM | |
| SCHEMBL31147237 | 0.79 | SRD5A2 (0.43) | SRD5A2SRD5A1KDM4EALDH1A1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3998833-A | CORROSION INHIBITORS, MICROBIOCIDES | PETROLITE CORPORATION (US) | 1976-12-21 | — | — | US | claimed |
| EP-4276534-A1 | MASK BLANK, RESIST PATTERN FORMING PROCESS AND CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION | Shin-Etsu Chemical Co., Ltd. (JP) | 2023-11-15 | — | — | EP | disclosed |
| CN-108084176-A | Preparation method of high-purity palonosetron hydrochloride | 昆明源瑞制药有限公司 | 2018-05-29 | — | — | CN | disclosed |
| WO-2016168450-A1 | ACETYLENIC CYANOENONES AS THERAPEUTICS FOR INFLAMMATION AND CARCINOGENESIS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2016-10-20 | — | — | WO | disclosed |
| CN-104788503-A | Ferrocene-quinolone amide compound as well as preparation method and application thereof | UNIV GUILIN MEDICAL | 2015-07-22 | — | — | CN | disclosed |
| CN-104744189-A | Method for preparing alpha-aryl acrylic acid by carbon dioxide | UNIV CHANGZHOU | 2015-07-01 | — | — | CN | disclosed |
| US-8846760-B2 | Dihydronaphthalene and naphthalene derivatives as N-formyl peptide receptor like-1 (FPRL-1) receptor modulators | ALLERGAN, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-20140128471-A1 | DIHYDRONAPHTHALENE AND NAPHTHALENE DERIVATIVES AS N-FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2014-05-08 | — | — | US | disclosed |
| CN-101638414-B | Peptidyl boronic acid, ester compound thereof, preparation method of peptidyl boronic acid and ester compound thereof, and use of peptidyl boronic acid and ester compound thereof | JIANGSU SIMCERE PHARMACEUTICAL | 2014-01-08 | — | — | CN | disclosed |
| US-7968601-B2 | Treating excess cortisol formation; obesity, cardiovascular disorders, glaucoma, osteoporosis, Alzheimer's Disease; antidiabetic agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2011-06-28 | — | — | US | disclosed |
| US-5276053-A | Dibenzothiopyranylamines | WARNER-LAMBERT COMPANY (US) | 1994-01-04 | — | — | US | disclosed |
| US-5180736-A | Treatment and prevention of brain disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-19 | — | — | US | disclosed |
| US-5071853-A | Amine-substituted hexahydroindeno(2,1-b)pyrroles, -indeno(2,1-c)pyridines or -indeno(2,1-d)azepines; cerebral ischemia or infarction | WARNER-LAMBERT COMPANY | 1991-12-10 | — | — | US | disclosed |
| US-4968677-A | PHYTOPATHOGENS | CIBA-GEIGY CORPORATION (US) | 1990-11-06 | — | — | US | disclosed |
| EP-0388977-A2 | Polycyclic amines useful as cerebrovascular agents | WARNER-LAMBERT COMPANY (US) | 1990-09-26 | — | — | EP | disclosed |
| US-4657581-A | AMIDE COMPOUNDS, OF DI OR TETRAHYDRO-1 NAPHTHOIC ACID | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1987-04-14 | — | — | US | disclosed |
| US-4089650-A | Use of Diels-Alder adducts of dihydro-nitrogen heterocyclic phosphoramidates as corrosion inhibitors | PETROLITE CORPORATION (US) | 1978-05-16 | — | — | US | disclosed |
| US-3998833-A | CORROSION INHIBITORS, MICROBIOCIDES | PETROLITE CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |
| US-3997293-A | Use of dihydro-nitrogen heterocyclic phosphoramidates as corrosion inhibitors | PETROLITE CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |
| US-3965264-A | DIELS-ALDER ADDUCT OF A PHOSPHORAMIDATE AND A DIENOPHILE | PETROLITE CORPORATION (US) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140128471-A1 | DIHYDRONAPHTHALENE AND NAPHTHALENE DERIVATIVES AS N-FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | FPR1, FPR2, FPR3 | SRD5A2 2583/4885SRD5A1 1642/4885KDM4E 4843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.