Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 4/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14527403 | 0.86 | GHSR (0.56) | GHSRALDH1A1KDM4EHPGDENPP2 | |
| SCHEMBL14526878 | 0.81 | KDM4E (0.63) | GHSRALDH1A1KDM4EHPGDENPP2 | |
| SCHEMBL7395927 | 0.81 | KDM4E (0.61) | ALDH1A1KDM4EHPGDENPP2HSD17B10 | |
| SCHEMBL14527441 | 0.79 | SIRT2 (0.47) | GHSRALDH1A1KDM4EHPGDENPP2 | |
| SCHEMBL31593940 | 0.79 | KDM4E (0.58) | GHSRALDH1A1KDM4EHPGDENPP2 | |
| SCHEMBL18000228 | 0.77 | BRAF (0.58) | GHSRCHRNA7CCNCCDK8BRAF | |
| SCHEMBL14527422 | 0.77 | CHEK2 (0.49) | ALDH1A1KDM4EHPGDENPP2HSD17B10 | |
| SCHEMBL2004886 | 0.75 | KDM4E (0.66) | ALDH1A1KDM4EHPGDENPP2HSD17B10 | |
| SCHEMBL232249 | 0.73 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDENPP2HSD17B10 | |
| SCHEMBL4102768 | 0.73 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDENPP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070093529-A1 | Diacylhydrazine derivatives | MERCK PATENT GMBH (DE) | 2007-04-26 | — | — | US | disclosed |
| US-20070093529-A1 | Diacylhydrazine derivatives | MERCK PATENT GMBH (DE) | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093529-A1 | Diacylhydrazine derivatives | BRAF, RAF1, NRAS | GHSR 3536/4885ALDH1A1 1014/4885KDM4E 2528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.