Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.64 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.61 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.61 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211677 | 0.86 | F2 (0.57) | TAS1R3TAS1R1SMYD3HDAC1HDAC2 | |
| SCHEMBL2004886 | 0.84 | KDM4E (0.66) | ALDH1A1HSD17B10KDM4EHPGDENPP2 | |
| SCHEMBL26345638 | 0.83 | ALDH1A1 (0.64) | ALDH1A1HSD17B10KDM4EHPGDENPP2 | |
| SCHEMBL4102768 | 0.83 | ALDH1A1 (0.64) | ALDH1A1HSD17B10KDM4EHPGDENPP2 | |
| SCHEMBL8403078 | 0.82 | TAS1R3 (0.64) | ALDH1A1HSD17B10KDM4EHPGDENPP2 | |
| SCHEMBL4164841 | 0.82 | TAS1R3 (0.56) | ALDH1A1HSD17B10KDM4EHPGDENPP2 | |
| SCHEMBL50552 | 0.80 | ALDH1A1 (0.70) | ALDH1A1HSD17B10KDM4EHPGDENPP2 | |
| SCHEMBL30201702 | 0.80 | ALDH1A1 (0.70) | ALDH1A1HSD17B10KDM4EHPGDENPP2 | |
| SCHEMBL14526878 | 0.79 | KDM4E (0.63) | ALDH1A1HSD17B10KDM4EHPGDENPP2 | |
| SCHEMBL19531859 | 0.79 | TAS1R3 (0.68) | ALDH1A1HSD17B10KDM4EHPGDENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12559455-B2 | Compound as a UBR box domain ligand | AUTOTAC INC. (KR) | 2026-02-24 | — | — | US | disclosed |
| US-20230174470-A1 | COMPOUND AS A UBR BOX DOMAIN LIGAND | AUTOTAC INC. (KR) | 2023-06-08 | — | — | US | disclosed |
| US-20230174470-A1 | COMPOUND AS A UBR BOX DOMAIN LIGAND | AUTOTAC INC. (KR) | 2023-06-08 | — | — | US | disclosed |
| WO-2023074936-A1 | BIFUNCTIONAL COMPOUND USING UBR BOX DOMAIN-BINDING LIGAND | 주식회사 오토텍바이오 | 2023-05-04 | — | — | WO | disclosed |
| EP-4144722-A1 | COMPOUND AS UBR BOX DOMAIN LIGAND | Autotac Inc. (KR) | 2023-03-08 | — | — | EP | disclosed |
| CN-115715285-A | Compounds as UBR box domain ligands | 奧土择破利悟 | 2023-02-24 | — | — | CN | disclosed |
| US-8778928-B2 | Indolyl-oxadiazolyl-diazabicyclononane derivatives and their medical and diagnostical use | DANPET AB (SE) | 2014-07-15 | — | — | US | disclosed |
| US-20120003153-A1 | NOVEL INDOLYL-OXADIAZOLYL-DIAZABICYCLONONANE DERIVATIVES AND THEIR MEDICAL AND DIAGNOSTICAL USE | NEUROSEARCH A/S (DK) | 2012-01-05 | — | — | US | disclosed |
| CN-102300574-A | Novel indolyl-oxadiazolyl-diazabicyclononane derivatives and their medical and diagnostical use | — | 2011-12-28 | — | — | CN | disclosed |
| CN-100537568-C | 6-substituted pyridoindolone derivatives, their preparation and therapeutic use | SANOFI AVENTIS (FR) | 2009-09-09 | — | — | CN | disclosed |
| WO-2005040157-A2 | NOVEL MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2005-05-06 | — | — | WO | disclosed |
| EP-1183252-B1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-18 | — | — | EP | disclosed |
| US-6492406-B1 | PROTEIN KINASE C INHIBITORS; ANTIINFLAMMATORY AND IMMUNO-SUPPRESSIVE AGENTS | ASTRAZENECA AB (SE) | 2002-12-10 | — | — | US | disclosed |
| EP-1183252-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071537-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2000-11-30 | — | — | WO | disclosed |
| CN-1056144-C | 6-heterocyclic-4-amino1,3,4,5-tetrahydrobenz{CD}indoles for treating motion sickness and vomiting | LILLY CO ELI (US) | 2000-09-06 | — | — | CN | disclosed |
| US-5750554-A | COMPOUNDS FOR TREATMENT OF ANXIETY, DEPRESSION, ANTISECRETORY AGENTS, HYPOTENSIVE AGENTS AND TREATMENT OF EATING PROBLEMS | ELI LILLY AND COMPANY (US) | 1998-05-12 | — | — | US | disclosed |
| US-5736562-A | MODIFY FUNCTION OF SEROTONIN IN MAMMALS | ELI LILLY AND COMPANY (US) | 1998-04-07 | — | — | US | disclosed |
| US-5674884-A | FOR TREATMENT OF SEROTONIN-RELATED DISORDERS | ELI LILLY AND COMPANY (US) | 1997-10-07 | — | — | US | disclosed |
| CN-1094724-A | 6-heterocycle-4-the amino-1,3,4 that is used for the treatment of motion sickness and vomiting sickness, 5-tetrahydro benzo [cd] indoles | LILLY CO ELI (US) | 1994-11-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174470-A1 | COMPOUND AS A UBR BOX DOMAIN LIGAND | UBR4, UBQLN2, UBTF | ALDH1A1 2317/4885HSD17B10 1933/4885KDM4E 1340/4885 |
| US-12559455-B2 | Compound as a UBR box domain ligand | UBR4, UBTF, UBQLN1 | ALDH1A1 1486/4885HSD17B10 1707/4885KDM4E 707/4885 |
| US-20120003153-A1 | NOVEL INDOLYL-OXADIAZOLYL-DIAZABICYCLONONANE DERIVATIVES AND THEIR MEDICAL AND DIAGNOSTICAL USE | CHRNA6, CHRNA10, CHRNA3 | ALDH1A1 1114/4885HSD17B10 1143/4885KDM4E 2986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.