Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14527691 | 0.86 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDGAANPSR1 | |
| SCHEMBL4591604 | 0.86 | KDM4E (0.54) | KDM4EALDH1A1HPGDGPR35GAA | |
| SCHEMBL4592847 | 0.85 | GPR35 (0.65) | KDM4EALDH1A1HPGDGPR35GAA | |
| SCHEMBL4592128 | 0.84 | GPR35 (0.50) | KDM4EALDH1A1HPGDGPR35GAA | |
| SCHEMBL4591940 | 0.79 | ALDH1A1 (0.67) | KDM4EALDH1A1HPGDGAANPSR1 | |
| SCHEMBL5161760 | 0.78 | ALDH1A1 (0.60) | KDM4EALDH1A1HPGDGPR35GAA | |
| SCHEMBL5157162 | 0.77 | MAPT (0.54) | KDM4EALDH1A1HPGDGAANPSR1 | |
| SCHEMBL4592690 | 0.77 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDGAANPSR1 | |
| SCHEMBL9437968 | 0.77 | TUBB4A (0.65) | KDM4EALDH1A1HPGDGAANPSR1 | |
| SCHEMBL4592062 | 0.76 | KDM4E (0.49) | KDM4EALDH1A1HPGDGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1779849-A1 | V-ATPase inhibitors for the treatment of septic shock | NIKEM RESEARCH S.R.L. (IT) | 2007-05-02 | — | — | EP | disclosed |