Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | CHAT | P28329 | 1/20 | 0.35 |
| ▸ | FGB | P02675 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15851430 | 0.74 | AURKA (0.53) | AURKAAURKBTTRCOMTSNCA | |
| SCHEMBL3828946 | 0.74 | AURKA (0.53) | AURKAAURKBTTRCOMTSNCA | |
| SCHEMBL22511324 | 0.74 | AURKA (0.53) | AURKAAURKBTTRCOMTSNCA | |
| SCHEMBL14201531 | 0.73 | AURKA (0.51) | AURKAAURKBTTRCOMTSNCA | |
| SCHEMBL9568585 | 0.71 | AURKB (0.58) | AURKAAURKBTTRCOMTSNCA | |
| SCHEMBL9568598 | 0.71 | AURKB (0.58) | AURKAAURKBTTRCOMTSNCA | |
| SCHEMBL9568549 | 0.71 | AURKB (0.58) | AURKAAURKBTTRCOMTSNCA | |
| SCHEMBL9568545 | 0.71 | AURKB (0.58) | AURKAAURKBTTRCOMTSNCA | |
| SCHEMBL20864368 | 0.71 | PKM (0.71) | ALDH1A1HSD17B10PKMBRD4SMN1; SMN2 | |
| SCHEMBL29383992 | 0.70 | TTR (0.67) | AURKAAURKBTTRCOMTSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1093015-B1 | IR-photographic sensitizing dyes | AGFA GRAPHICS NV (BE) | 2007-05-23 | — | — | EP | disclosed |