Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 2/20 | 0.43 |
| ▸ | CHAT | P28329 | 1/20 | 0.43 |
| ▸ | COMT | P21964 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15851430 | 0.89 | AURKA (0.53) | AURKAAURKBTTRALDH1A1MAPT | |
| SCHEMBL1710169 | 0.87 | TYMS (0.54) | AURKAAURKBTTRALDH1A1MAPT | |
| SCHEMBL30203973 | 0.87 | TYMS (0.54) | AURKAAURKBTTRALDH1A1MAPT | |
| SCHEMBL8291788 | 0.86 | POLB (0.56) | AURKAAURKBALDH1A1MAPTKDM4E | |
| SCHEMBL9006326 | 0.80 | CYP1B1 (0.61) | ALDH1A1MAPTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL12889338 | 0.79 | CYP1A2 (0.45) | AURKAAURKBTTRALDH1A1CES1 | |
| SCHEMBL9568545 | 0.78 | AURKB (0.58) | AURKAAURKBTTRALDH1A1SNCA | |
| SCHEMBL9568585 | 0.78 | AURKB (0.58) | AURKAAURKBTTRALDH1A1SNCA | |
| SCHEMBL9568549 | 0.78 | AURKB (0.58) | AURKAAURKBTTRALDH1A1SMN1; SMN2 | |
| SCHEMBL9568598 | 0.78 | AURKB (0.58) | AURKAAURKBTTRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7736707-B2 | Birefringent film, polycyclic compound, coating liquid, and image display device | NITTO DENKO CORPORATION (JP) | 2010-06-15 | — | — | US | disclosed |
| US-7736707-B2 | Birefringent film, polycyclic compound, coating liquid, and image display device | NITTO DENKO CORPORATION (JP) | 2010-06-15 | — | — | US | disclosed |
| US-20090059370-A1 | BIREFRINGENT FILM AND METHOD OF PRODUCING THE SAME | NITTO DENKO CORPORATION (JP) | 2009-03-05 | — | — | US | disclosed |
| US-20090059370-A1 | BIREFRINGENT FILM AND METHOD OF PRODUCING THE SAME | NITTO DENKO CORPORATION (JP) | 2009-03-05 | — | — | US | disclosed |
| US-20090059370-A1 | BIREFRINGENT FILM AND METHOD OF PRODUCING THE SAME | NITTO DENKO CORPORATION (JP) | 2009-03-05 | — | — | US | disclosed |
| US-20080224095-A1 | BIREFRINGENT FILM, POLYCYCLIC COMPOUND, COATING LIQUID, AND IMAGE DISPLAY DEVICE | NITTO DENKO CORPORATION (JP) | 2008-09-18 | — | — | US | disclosed |
| US-20080224095-A1 | BIREFRINGENT FILM, POLYCYCLIC COMPOUND, COATING LIQUID, AND IMAGE DISPLAY DEVICE | NITTO DENKO CORPORATION (JP) | 2008-09-18 | — | — | US | disclosed |
| US-20070248771-A1 | Acenaphtho[1,2-b]quinoxaline sulfo-and carboxy-derivative, lyotropic liquid crystal system, optically anisotropic film and method thereof and laminated optical film | NITTO DENKO CORPORATION | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080224095-A1 | BIREFRINGENT FILM, POLYCYCLIC COMPOUND, COATING LIQUID, AND IMAGE DISPLAY DEVICE | CIAPIN1, PYM1, AQP1 | AURKA 431/4885AURKB 1126/4885TTR 2761/4885 |
| US-20070248771-A1 | Acenaphtho[1,2-b]quinoxaline sulfo-and carboxy-derivative, lyotropic liquid crystal system, optically anisotropic film and method thereof and laminated optical film | XDH, ACE2, PNPO | AURKA 1418/4885AURKB 1482/4885TTR 996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.