Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14531655 | 0.84 | RAB9A (0.45) | RAB9ASMN1; SMN2MAPTTP53NPC1 | |
| SCHEMBL12582232 | 0.83 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2ALPLMAPTTP53 | |
| SCHEMBL2103537 | 0.81 | RXFP1 (0.49) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| Lithium SCHEMBL31133404 | 0.81 | SCN9A (0.46) | RAB9ASMN1; SMN2MAPTTP53NPC1 | |
| SCHEMBL10269165 | 0.74 | TARBP2 (0.50) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL27164122 | 0.72 | L3MBTL1 (0.36) | RAB9ASMN1; SMN2NPC1ALDH1A1MEN1 | |
| SCHEMBL7431062 | 0.72 | KMO (0.52) | RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL260602 | 0.71 | ALDH1A1 (0.51) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL12907953 | 0.70 | SCN9A (0.61) | RAB9ASMN1; SMN2MAPTTP53NPC1 | |
| SCHEMBL12582233 | 0.70 | RAB9A (0.48) | RAB9ASMN1; SMN2ALPLMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056469-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |