Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 11/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13613826 | 0.88 | ALDH1A1 (0.39) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL13613827 | 0.84 | KMT2A (0.38) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL13613813 | 0.83 | TLR7 (0.38) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL13613810 | 0.82 | TLR7 (0.39) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL13613812 | 0.82 | FAAH (0.42) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL4338051 | 0.81 | TLR7 (0.40) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL13613811 | 0.80 | TLR7 (0.39) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL13613815 | 0.80 | LCK (0.36) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL13613823 | 0.79 | LMNA (0.41) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL13613825 | 0.78 | IDO1 (0.37) | TLR7LMNAPOLBHRH2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214675-B2 | Urea substituted imidazoquinoline ethers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-05-08 | — | — | US | disclosed |