Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | VHL | P40337 | 1/20 | 0.39 |
| ▸ | ELOC | Q15369 | 1/20 | 0.39 |
| ▸ | ELOB | Q15370 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9776610 | 0.91 | TSHR (0.56) | TSHRVHLELOCELOBLTA4H | |
| SCHEMBL5930991 | 0.89 | PTGS1 (0.44) | TSHR | |
| SCHEMBL3236662 | 0.83 | TSHR (0.46) | TSHRPRSS1PRSS2PRSS3VHL | |
| SCHEMBL13539012 | 0.83 | CYP1A2 (0.50) | CA1CA2 | |
| SCHEMBL1002201 | 0.82 | CES2 (0.42) | TSHR | |
| SCHEMBL9396256 | 0.80 | TSHR (0.48) | TSHRPRSS1PRSS2PRSS3VHL | |
| SCHEMBL15045345 | 0.80 | TSHR (0.48) | TSHRPRSS1PRSS2PRSS3VHL | |
| SCHEMBL14417182 | 0.79 | PRSS1 (0.43) | TSHRPRSS1PRSS2PRSS3VHL | |
| SCHEMBL8746277 | 0.79 | TSHR (0.42) | TSHRPRSS1PRSS2PRSS3VHL | |
| SCHEMBL40702 | 0.79 | NOS3 (0.42) | TSHRPRSS1PRSS2PRSS3VHL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113233994-B | Alpha-diimine compound with multiple hydroxyl groups, complex, load and application thereof | 河北工业大学 | 2023-01-06 | — | — | CN | claimed |
| CN-113233994-B | Alpha-diimine compound with multiple hydroxyl groups, complex, load and application thereof | 河北工业大学 | 2023-01-06 | — | — | CN | disclosed |
| CN-113233994-A | Alpha-diimine compound with multiple hydroxyl groups, complex, load and application thereof | 河北工业大学 | 2021-08-10 | — | — | CN | disclosed |
| CN-113185415-A | Aromatic amine with multiple hydroxyl groups and pyridine diimine compound, complex and load thereof | 河北工业大学 | 2021-07-30 | — | — | CN | disclosed |
| US-20070099876-A1 | Target directed chemotherapy of tumours of the sexual organs | TRIN GMBH (CH) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099876-A1 | Target directed chemotherapy of tumours of the sexual organs | GPER1, SHBG, GNRHR | TSHR 1181/4885PRSS1 2892/4885PRSS2 3053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.