Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 3/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407329 | 0.89 | POLB (0.35) | POLBMAPTESR1ARESR2 | |
| SCHEMBL9757494 | 0.85 | SHBG (0.34) | SHBGESR1ARESR2 | |
| SCHEMBL23768743 | 0.78 | ESR1 (0.32) | POLBMAPTSHBGESR1AR | |
| SCHEMBL20851724 | 0.77 | SHBG (0.41) | POLBSHBGESR1ARESR2 | |
| SCHEMBL7938353 | 0.76 | POLB (0.34) | POLBMAPT | |
| SCHEMBL9273347 | 0.76 | POLB (0.34) | POLBMAPT | |
| SCHEMBL7949847 | 0.75 | POLB (0.34) | POLBMAPTESR1ARESR2 | |
| SCHEMBL5891966 | 0.75 | PGR (0.36) | POLBMAPTAR | |
| SCHEMBL8410110 | 0.75 | PGR (0.36) | POLBMAPTAR | |
| SCHEMBL7944854 | 0.75 | POLB (0.33) | POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226155-B1 | 18-NOR-STEROIDS AS SELECTIVELY ACTIVE ESTROGENS | BAYER SCHERING PHARMA AG (DE) | 2007-05-02 | — | — | EP | disclosed |