Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29836179 | 0.80 | SMN1; SMN2 (0.48) | ALDH1A1GAAHSP90AB1SMN1; SMN2P2RX7 | |
| SCHEMBL14186623 | 0.80 | GAA (0.46) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL3967997 | 0.80 | SMN1; SMN2 (0.48) | ALDH1A1GAAHSP90AB1SMN1; SMN2P2RX7 | |
| SCHEMBL25689240 | 0.79 | P2RX7 (0.45) | ALDH1A1KDM4EGLAHPGDHSP90AB1 | |
| SCHEMBL3625062 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL8115284 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL909006 | 0.78 | P2RX7 (0.45) | ALDH1A1KDM4EGLAGAAHPGD | |
| SCHEMBL3144672 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL837237 | 0.78 | P2RX7 (0.48) | ALDH1A1KDM4EKMT2AP2RX7L3MBTL1 | |
| SCHEMBL30883124 | 0.78 | P2RX7 (0.45) | ALDH1A1KDM4EGLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007054831-A2 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | METHYLGENE, INC. (CA) | 2007-05-18 | — | — | WO | disclosed |