Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NPY4R | P50391 | 9/20 | 0.36 |
| ▸ | NPY1R | P25929 | 5/20 | 0.36 |
| ▸ | NPY2R | P49146 | 4/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.36 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | ANPEP | P15144 | 3/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10190207 | 0.91 | DPP7 (0.44) | NOS1NPY4RNPY1RNPY2RNPY5R | |
| Hydrochloric Acid SCHEMBL607606 | 0.90 | DPP7 (0.43) | NOS1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL608402 | 0.80 | NOS1 (0.49) | NOS1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL3164624 | 0.77 | LONP1 (0.39) | — | |
| SCHEMBL608401 | 0.76 | NOS1 (0.41) | NOS1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL3164228 | 0.75 | PSMB5 (0.47) | — | |
| Nitroarginine SCHEMBL345312 | 0.74 | NOS1 (0.48) | NOS1 | |
| SCHEMBL5983469 | 0.74 | NOS1 (0.46) | NOS1DPP7 | |
| SCHEMBL607060 | 0.74 | NOS1 (0.46) | NOS1DPP7 | |
| Nitroarginine SCHEMBL881062 | 0.74 | NOS1 (0.48) | NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223745-B2 | Proteasome inhibitors and methods of using the same | CEPHALON, INC. (US) | 2007-05-29 | — | — | US | disclosed |