Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK5 | Q8IW41 | 13/20 | 0.54 |
| ▸ | AURKA | O14965 | 5/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8246471 | 0.89 | AURKA (0.62) | MAPKAPK5AURKAFYNPTK6AURKB | |
| SCHEMBL13954861 | 0.86 | AURKB (0.56) | MAPKAPK5AURKAFYNPTK6AURKB | |
| SCHEMBL14530182 | 0.81 | AURKA (0.53) | MAPKAPK5AURKAFYNAURKB | |
| SCHEMBL14536959 | 0.81 | TTK (0.54) | MAPKAPK5AURKAFYNAURKB | |
| SCHEMBL27359527 | 0.81 | FYN (0.62) | MAPKAPK5AURKAFYNPTK6 | |
| SCHEMBL14536833 | 0.80 | AURKA (0.48) | MAPKAPK5AURKAFYNAURKB | |
| SCHEMBL14537084 | 0.79 | AURKA (0.46) | AURKAAURKB | |
| SCHEMBL27359540 | 0.79 | MAPKAPK5 (0.60) | MAPKAPK5FYNPTK6AURKB | |
| SCHEMBL8240973 | 0.78 | MAPKAPK5 (0.64) | MAPKAPK5AURKAFYNAURKB | |
| SCHEMBL14530020 | 0.78 | AURKA (0.62) | MAPKAPK5AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056468-A1 | METHODS FOR INHIBITING PROTEIN KINASES | SCHERING CORPORATION (US) | 2007-05-18 | — | — | WO | disclosed |