Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 14/20 | 0.55 |
| ▸ | FLT3 | P36888 | 3/20 | 0.53 |
| ▸ | AURKA | O14965 | 3/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247604 | 0.86 | TTK (0.58) | TTKFLT3AURKAAURKB | |
| SCHEMBL14536949 | 0.85 | TTK (0.46) | TTKFLT3AURKAAURKB | |
| SCHEMBL14537008 | 0.82 | AURKA (0.46) | TTKFLT3AURKAAURKB | |
| SCHEMBL5408560 | 0.80 | TTK (0.65) | TTKFLT3 | |
| SCHEMBL14537009 | 0.77 | FLT3 (0.46) | TTKFLT3AURKAAURKB | |
| SCHEMBL14530182 | 0.76 | AURKA (0.53) | TTKFLT3AURKAAURKB | |
| SCHEMBL14536959 | 0.76 | TTK (0.54) | TTKAURKAAURKB | |
| SCHEMBL14529894 | 0.76 | AURKA (0.42) | TTKFLT3AURKAAURKB | |
| SCHEMBL14529892 | 0.76 | TTK (0.47) | TTKAURKAAURKB | |
| SCHEMBL5394360 | 0.75 | FLT3 (0.56) | TTKFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056468-A1 | METHODS FOR INHIBITING PROTEIN KINASES | SCHERING CORPORATION (US) | 2007-05-18 | — | — | WO | disclosed |