Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BPTF | Q12830 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13039605 | 0.81 | ATM (0.50) | ALDH1A1ATML3MBTL1KMT2ALMNA | |
| SCHEMBL4503439 | 0.79 | ATM (0.48) | ALDH1A1ATML3MBTL1KMT2APOLB | |
| SCHEMBL14538084 | 0.79 | ATM (0.48) | ALDH1A1ATML3MBTL1KMT2APOLB | |
| SCHEMBL23144568 | 0.77 | ALDH1A1 (0.58) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL19703776 | 0.77 | ALDH1A1 (0.58) | ALDH1A1ATML3MBTL1KDM4EKMT2A | |
| SCHEMBL14538019 | 0.75 | ACHE (0.54) | ALDH1A1L3MBTL1KDM4EKMT2A | |
| SCHEMBL10313328 | 0.74 | KMT2A (0.46) | ALDH1A1L3MBTL1KMT2APOLB | |
| SCHEMBL1713072 | 0.73 | ALDH1A1 (0.42) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL19704627 | 0.72 | CPN1 (0.40) | ALDH1A1L3MBTL1DPP4DPP7KDM4E | |
| SCHEMBL25934762 | 0.72 | EPHX2 (0.41) | ALDH1A1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007059116-A2 | GELDANAMYCIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | ABRAXIS BIOSCIENCE, INC. (US) | 2007-05-24 | — | — | WO | disclosed |