Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4503439 | 1.00 | ATM (0.48) | ATMRAB9AHPGDPOLBMAPT | |
| SCHEMBL13039605 | 0.98 | ATM (0.50) | ATMRAB9AHPGDPOLBMAPT | |
| SCHEMBL14538019 | 0.82 | ACHE (0.54) | ALDH1A1MEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL14538018 | 0.79 | ALDH1A1 (0.36) | ATMPOLBALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL5181688 | 0.78 | TPSAB1 (0.51) | POLBALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL28716383 | 0.78 | ALDH1A1 (0.50) | ATMRAB9AHPGDPOLBALDH1A1 | |
| SCHEMBL14538081 | 0.78 | L3MBTL1 (0.70) | RAB9AHPGDPOLBALDH1A1L3MBTL1 | |
| SCHEMBL1220310 | 0.77 | KMT2A (0.52) | ATMRAB9AHPGDPOLBMAPT | |
| SCHEMBL13450960 | 0.77 | KMT2A (0.52) | ATMRAB9AHPGDPOLBMAPT | |
| SCHEMBL15919877 | 0.77 | ATM (0.48) | ATMRAB9AHPGDPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007059116-A2 | GELDANAMYCIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | ABRAXIS BIOSCIENCE, INC. (US) | 2007-05-24 | — | — | WO | disclosed |