Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | YAP1 | P46937 | 1/20 | 0.42 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | BPTF | Q12830 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GPX4 | P36969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5564424 | 0.92 | ALDH1A1 (0.67) | ALDH1A1LMNAYAP1TEAD4POLB | |
| SCHEMBL23144922 | 0.81 | ALDH1A1 (0.58) | ALDH1A1LMNAYAP1TEAD4POLB | |
| SCHEMBL16145380 | 0.80 | ALDH1A1 (0.57) | ALDH1A1LMNAYAP1TEAD4POLB | |
| SCHEMBL16083090 | 0.80 | ALDH1A1 (0.57) | ALDH1A1LMNAYAP1TEAD4POLB | |
| SCHEMBL16083084 | 0.80 | ALDH1A1 (0.57) | ALDH1A1LMNAYAP1TEAD4POLB | |
| SCHEMBL23144513 | 0.79 | ALDH1A1 (0.59) | ALDH1A1LMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL11839944 | 0.79 | ALDH1A1 (0.85) | ALDH1A1LMNAYAP1TEAD4POLB | |
| SCHEMBL69354 | 0.79 | — | — | |
| SCHEMBL224023 | 0.79 | — | — | |
| SCHEMBL227972 | 0.77 | ALDH1A1 (0.56) | ALDH1A1LMNAPOLBHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220387411-A1 | TARGETED AUTOPHAGY CONJUGATES AND METHODS | VULCAN BIO CORPORATION | 2022-12-08 | — | — | US | disclosed |
| US-20220387411-A1 | TARGETED AUTOPHAGY CONJUGATES AND METHODS | VULCAN BIO CORPORATION | 2022-12-08 | — | — | US | disclosed |
| EP-4034557-A1 | TARGETED AUTOPHAGY CONJUGATES AND METHODS | Frontier Medicines Corporation (US) | 2022-08-03 | — | — | EP | disclosed |
| WO-2021061858-A1 | TARGETED AUTOPHAGY CONJUGATES AND METHODS | FRONTIER MEDICINES CORPORATION (US) | 2021-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220387411-A1 | TARGETED AUTOPHAGY CONJUGATES AND METHODS | ATG7, BECN1, SQSTM1 | ALDH1A1 3444/4885LMNA 1279/4885YAP1 1481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.