Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.57 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.32 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.32 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.32 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3510339 | 1.00 | S1PR1 (0.57) | S1PR1S1PR3S1PR5HPGDALDH1A1 | |
| SCHEMBL3508875 | 0.97 | S1PR1 (0.54) | S1PR1S1PR3S1PR5HPGDALDH1A1 | |
| SCHEMBL3513396 | 0.97 | S1PR1 (0.54) | S1PR1S1PR3S1PR5HPGDALDH1A1 | |
| SCHEMBL1454028 | 0.93 | S1PR1 (0.57) | S1PR1S1PR3S1PR5HPGDALDH1A1 | |
| SCHEMBL1454717 | 0.93 | S1PR1 (0.57) | S1PR1S1PR3S1PR5HPGDALDH1A1 | |
| SCHEMBL1453320 | 0.92 | S1PR1 (0.56) | S1PR1S1PR3S1PR5ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL1454325 | 0.92 | S1PR1 (0.56) | S1PR1S1PR3S1PR5HPGDALDH1A1 | |
| SCHEMBL3512608 | 0.90 | S1PR1 (0.54) | S1PR1S1PR3S1PR5HPGDALDH1A1 | |
| SCHEMBL3509776 | 0.90 | S1PR1 (0.54) | S1PR1S1PR3S1PR5HPGDALDH1A1 | |
| SCHEMBL13165813 | 0.90 | S1PR1 (0.53) | S1PR1S1PR3S1PR5ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915994-B1 | CYCLIC AMINE DERIVATIVES IN COMBINATION WITH PPAR REGULATORS | DAIICHI SANKYO CO LTD (JP) | 2012-08-01 | — | — | EP | claimed |
| EP-1782804-B1 | MEDICINAL COMPOSITION, COMPRISING A HMG-CoA REDUCTASE INHIBITOR AND AN AMINO ALCOHOL DERIVATIVE, AS IMMUNOSUPPRESSANT | DAIICHI SANKYO CO LTD (JP) | 2011-12-28 | — | — | EP | claimed |
| US-20080153882-A1 | Pharmaceutical Composition Comprising Ppar Regulator | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-06-26 | — | — | US | claimed |
| EP-1915994-A1 | CYCLIC AMINE DERIVATIVE CONTAINING PPAR REGULATOR | Sankyo Company, Limited (JP) | 2008-04-30 | — | — | EP | claimed |
| US-20070149597-A1 | Medicinal composition as immunosuppressant | SANKYO COMPANY, LIMITED (JP) | 2007-06-28 | — | — | US | claimed |
| EP-1782804-A1 | MEDICINAL COMPOSITION AS IMMUNOSUPPRESSANT | Sankyo Company, Limited (JP) | 2007-05-09 | — | — | EP | claimed |
| EP-2045325-B1 | DRUG-PHOSPHORYLATING ENZYME | DAIICHI SANKYO CO LTD (JP) | 2012-09-19 | — | — | EP | disclosed |
| EP-1915994-B1 | CYCLIC AMINE DERIVATIVES IN COMBINATION WITH PPAR REGULATORS | DAIICHI SANKYO CO LTD (JP) | 2012-08-01 | — | — | EP | disclosed |
| EP-1782804-B1 | MEDICINAL COMPOSITION, COMPRISING A HMG-CoA REDUCTASE INHIBITOR AND AN AMINO ALCOHOL DERIVATIVE, AS IMMUNOSUPPRESSANT | DAIICHI SANKYO CO LTD (JP) | 2011-12-28 | — | — | EP | disclosed |
| US-7910617-B2 | Method for suppressing the number of peripheral blood lymphocytes using an amino alcohol compound | SANKYO COMPANY, LIMITED (JP) | 2011-03-22 | — | — | US | disclosed |
| US-20100248227-A1 | DRUG-PHOSPHORYLATING ENZYME | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-09-30 | — | — | US | disclosed |
| EP-2045325-A1 | DRUG-PHOSPHORYLATING ENZYME | Daiichi Sankyo Company, Limited (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-20080153882-A1 | Pharmaceutical Composition Comprising Ppar Regulator | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-06-26 | — | — | US | disclosed |
| EP-1915994-A1 | CYCLIC AMINE DERIVATIVE CONTAINING PPAR REGULATOR | Sankyo Company, Limited (JP) | 2008-04-30 | — | — | EP | disclosed |
| US-20070191468-A1 | Amino alcohol compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20070149597-A1 | Medicinal composition as immunosuppressant | SANKYO COMPANY, LIMITED (JP) | 2007-06-28 | — | — | US | disclosed |
| EP-1782804-A1 | MEDICINAL COMPOSITION AS IMMUNOSUPPRESSANT | Sankyo Company, Limited (JP) | 2007-05-09 | — | — | EP | disclosed |
| EP-1733724-A1 | AMINO ALCOHOL COMPOUND | Sankyo Company, Limited (JP) | 2006-12-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153882-A1 | Pharmaceutical Composition Comprising Ppar Regulator | PPARG, PPARA, PPARD | S1PR1 282/4885S1PR3 281/4885S1PR5 725/4885 |
| US-20070191468-A1 | Amino alcohol compound | ADH1A, ADH1C, BCAT1 | S1PR1 490/4885S1PR3 815/4885S1PR5 1515/4885 |
| US-20070149597-A1 | Medicinal composition as immunosuppressant | HMGCR, SHMT1, CYP11B1 | S1PR1 361/4885S1PR3 550/4885S1PR5 1010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.