Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 7/20 | 0.35 |
| ▸ | DRD3 | P35462 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | PLD2 | O14939 | 1/20 | 0.34 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.34 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14574 | 0.90 | DRD2 (0.36) | ADRA2CDRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL14463 | 0.89 | DRD2 (0.44) | ADRA2CDRD2DRD3FAAHCAMK2D | |
| SCHEMBL13698 | 0.83 | DRD2 (0.37) | DRD2DRD3KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8076 | 0.83 | DRD2 (0.37) | DRD2DRD3KDM4EALDH1A1HSD17B10 | |
| SCHEMBL12061561 | 0.79 | SLC6A4 (0.43) | MEN1KMT2A | |
| SCHEMBL17484485 | 0.79 | SLC6A4 (0.43) | MEN1KMT2A | |
| SCHEMBL12062415 | 0.78 | CHRM1 (0.48) | DRD2KDM4EALDH1A1HSD17B10PLD1 | |
| SCHEMBL14077 | 0.75 | SLC6A4 (0.47) | DRD2DRD3HTR1AHTR2AMEN1 | |
| SCHEMBL14551 | 0.74 | ADRA1D (0.52) | DRD2DRD3ALDH1A1HTR1AHTR2A | |
| SCHEMBL14035 | 0.72 | SLC6A4 (0.39) | KDM4EALDH1A1HSD17B10MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047319-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |